Structure biological aspects

Synthetic, structural, reactive, and biological aspects of novel tetraazabicyclooc-tanes 95F379. 

Poignard P, Saphire EO, Parren PW, Burton DR (2001) gpl20 Biologic aspects of structural features. Annu Rev Immunol 19 253-274... 

This report covers the synthetic and structural aspects of the subiect with discussion of the biological aspects included where relevant It covers the 1970 literature 2S4pp 16 00 (Still eveilsbie Vo 1 14 50 Vof 2 6 00)... 

Christianson D (1991) Structural biology of zinc. In Anfinsen C, Richards F, Edsall J, Eisenberg D (eds) Advances in protein chemistry. Metalloproteins structural aspects, vol 42. Academic Press, p 281... 

Molybdenum co-factor (Moco), 77 33 Molybdenum complexes, 26 927-929, 949 Molybdenum(III) complexes, 17 26-27 Molybdenum compounds, 17 19-43 in advanced structural and heating materials, 17 38-39 in anticorrosion agents, 17 39 biological aspects of, 17 31-34 biological uses for, 17 39-40 biomedical uses for, 17 40 catalytic applications of, 17 38 chemistry of, 17 29-31... 

The structural variety of biologically active esters (mostly but not exclusively drugs) is sufficiently great to allow their classification into representative groups, as discussed below. Over the years, a number of published reviews have presented biological aspects of ester hydrolysis and discussed some selected examples [1][2][75][76],... 

The resultant model is subjected to validation, in purely structural and biological aspects. For stereochemical quality, PROCHECK (73), PROVE (74), and Whatlf (75) are among the widely used programs. Programs such as Errat... 

The last chapter, by David W. Christianson, on the structural biology of zinc analyzes the huge literature in this area. The discussion of the structural aspects of zinc-containing proteins, as the discussions of the other metalloproteins in the four preceding chapters, is at a level of structural detail that would not have been possible even five years ago. In... 

Jahn, W. (1999) Review chemical aspects of the use of gold clusters in structural biology. J. Struct. Biol. 127, 106-112. 

Reilly TM, Mousa SA, Seetharam R, Racanelli AL. Recombinant plasminogen activator inhibitor type I a review of structural, functional, and biological aspects. Blood Coag Fibrinol 1994 5(l) 78 83. 

A knowledge of the structure of the H2—activating site is not only important for an understanding of the mechanism of action of the enzyme but is relevant for practical applications since it may provide clues on how to improve on, e.g., 02—and pH-instability. From a different perspective the active site may be a model to be mimicked by the inorganic chemist thus altogether eliminating the biological aspects of the problem. 

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