Stromal-derived factor 1 SDF

Fedyk ER, Ryyan DH, Ritterman I, Springer TA. Maturation decreases responsiveness of human bone marrow B lineage cells to stromal-derived factor 1 (SDF-1). J Leukoc Biol 1999 66(4) 667-673. 

Pan J., Mestas J., Burdick M. D., et al. (2006) Stromal derived factor-1 (SDF-1/ CXCL12) and CXCR4 in renal cell carcinoma metastasis. Mol Cancer. 5, 56. 

Wysoczynski, M., Kuda, M., Ratajczak, J., and Ratajczak, M.Z. (2007) Cleavage fragments of the third complement component (C3) enhance stromal derived factor-1 (SDF-l)-mediated platelet production during reactive postbleeding thrombocytosis. Leukemia, 21, 973-982. 

Bleul CC, Fuhlbrigge RC, Casasnovas JM, Aiuti A, Springer TA. A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1). J Exp Med 1996 184 1101-9. 

The murine stromal-derived factor-la (SDF-1)/CXCL12 was originally cloned from a cDNA library derived from the bone marrow stromal cell tine ST2 by a method to clone cDNAs that carry specific amino terminal signal sequences, such as those encoding intercellular signaling-transducing molecules... 

Hodohara K, Fujii N, Yamamoto N, Kaushansky K. Stromal cell-derived factor-1 (SDF-1) acts together with thrombopoietin to enhance the development of mega-karyocytic progenitor cells (CFU-MK). Blood 2000 95(3) 769-775. 

Valenzuela-Femandez A, Planchenault T, Baleux F, et al. Leukocyte elastase negatively regulates Stromal cell-derived factor-1 (SDF-1)/CXCR4 binding and functions by amino-terminal processing of SDF-1 and CXCR4. J Biol Chem 2002 277(18) 15677-15689. 

Kanbe K, Takemura T, Takeuchi K, Chen Q, Takagishi K, Inoue K. Synovectomy reduces stromal-cell-derived factor-1 (SDF-1) which is involved in the destruction of cartilage in osteoarthritis and rheumatoid arthritis. J Bone Joint Surg Br 2004 86(2) 296-300. 

List some of the roles of stromal cell-derived factor 1 (SDF-1) in CNS development and homeostasis. 

Majka, M., Ratajczak, J., et al. (2000). Binding of stromal derived factor-lalpha (SDF-lalpha) to CXCR4 chemokine receptor in normal human megakaryoblasts but not in platelets induces phosphorylation of mitogen-activated protein kinase p42/44 (MAPK), ELK-1 transcription factor and serine/threonine kinase AKT. Eur J Haematol 64(3) 164—72. 

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