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Stratification 1280 Subject

The randomization scheme assigns a therapy randomly across a study population based on various stratification factors such as site, blocking factor, and perhaps subject demographics. There is no actual patient assignment information in this data table. Here is an example of a randomization scheme with a block size of four and a treatment ratio of 2 2 ... [Pg.38]

The systems described until now have no stratification. In heat storages with stratification the lower layer is subject to large temperature changes while... [Pg.296]

Return now to the assertions of the Introduction. The explanation of assertion (1) was pointed out previously. Assertion (2), that the PDT is a practical computational tool, was the subject of Sect. 9.2.3. See especially the discussion "the general computational tricks work for the PDT also, emphasizing the general statistical methods of stratification and importance weighting, and their correspondence to the natural theoretical analyses of the PDT partition function. [Pg.347]

Bias in subject selection may not be avoided simply by randomisation. Randomisation will avoid weighted allocation to one treatment regimen rather than another, but it will not avoid selection of the wrong kind of subject in the first place, which will subsequently affect the degree to which the data can be extrapolated. Thus, an investigator may have a preconceived idea about the safety of a drug or about its effectiveness in a particular subset of subjects who nonetheless meet the entry criteria. This prejudice may be avoided by stratification of subjects... [Pg.226]

Electrodecantation is a stratification phenomenon that may take place when colloidal dispersions are subjected to an electric field between vertical membranes permeable to ions but not to colloids. This phenomenon was first observed in 1923 by W. Pauli of Austria (Ref 21)... [Pg.705]

Figure 4. The longitudinal vortex. A longitudinal vortex showing laminar flow about the central axis. The coldest water filaments are always closest to the central axis of flow. Thermal stratification occurs even with minimal differences in water temperature. The central core water is subjected to the least turbulence and acclerates ahead, drawing the rest of the water body in its wake. Figure 4. The longitudinal vortex. A longitudinal vortex showing laminar flow about the central axis. The coldest water filaments are always closest to the central axis of flow. Thermal stratification occurs even with minimal differences in water temperature. The central core water is subjected to the least turbulence and acclerates ahead, drawing the rest of the water body in its wake.
TIA-related infarctions on DWI can be predicted on the basis of certain clinical TIA features. Transient motor symptoms, preceding non-stereotypic attacks, the presence of an established cause of stroke, and presentation with aphasia are independent predictors of infarction on DWI (Ay et al. 2002 Crisostomo et al. 2003). In contrast, limb paresthesias, slurred speech, and brief attacks of dizziness or imbalance are not associated with occurrence of infarction. Of note, most symptoms that are not associated with infarction on DWI are based on patients subjective feelings and sensations in contrast to motor deficit or aphasia, it is not possible to objectively assess such symptoms and mark the brain as their origin. Of particular relevance to this point is that, according to a recent study, the independent predictors of infarction on DWI such as motor deficit and speech impairment are also independently associated with increased risk of stroke after TIA (Johnston et al. 2003), suggesting a potential role for DWI in the risk stratification for stroke following TIA. [Pg.190]

If appropriate, pharmacokinetic parameters were compared descriptively between age groups (with/ without stratification), between genders (with/without stratification), and between fasted and fed subjects (with/without stratification and individually). Although not intending to show bioequivalence, the 90 % confidence intervals (Cl) for the differences in the log transformed exposure measurements were calculated. [Pg.668]

INTRODUCTION 14 PESTICIDE CATEGORIES 15 PESTICIDE HANDLERS 15 Agricultural Pesticide Handlers 15 Tasks Performed by an Individual 16 Factors Affecting Exposure 16 Residential and Institutional Pesticide Handlers 18 Families of Pesticide Handlers 19 STUDY DESIGN CONSIDERATIONS 20 Worker Stratification 21 Routes of Exposure 21 Respiratory Exposure 21 Dermal Exposure 21 Sampling Strategy Selection 21 Statistical Analysis 22 PROTECTION OF HUMAN SUBJECTS 22 PESTICIDE EXPOSURE MONITORING METHODS 23 Passive Dosimetry 23... [Pg.13]


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