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Stem Cells Engineering for Cell-Based Therapy

Stem Cell Engineering for Cell-Based Therapy... [Pg.33]

Reproduced with permission from the Institute of Physics Publishing Ltd. Taupin, P. Stem cell engineering for cell-based therapy. Journal of Neural Engineering (2007) 4(3) R59-63. Copyright 2007, the Institute of Physics Publishing Ltd. http //jne.iop.org. [Pg.38]

Similar to stem-cell-based therapies, many technical challenges need to be tackled. Biological challenges include, for example, how to identify stem cells, how to culture stem cells, how to control their differentiation, and how to follow their fate after implantation. Engineering challenges must also be addressed, which are essential to the clinical and commercial success. These include ... [Pg.411]

Yamada, Y, Nakamura, S., Ito, K., Sugito, T, Yoshimi, R., Nagasaka, T., Ueda, M., 2010. A feasibility of useful cell-based therapy by bone regeneration with deciduous tooth stem cells, dental pulp stem ceUs, or bone-marrow-derived mesenchymal stem cehs for chnical study using tissue engineering technology. Tissue Eng. Part A 16, 1891-1900. [Pg.82]

In conclusion, we have shown that successful treatment of MI and I/R AKI with MSC holds substantial promise for the development of novel, MSC-based interventions that can improve the treatment of severe, and still largely therapy-resistant, clinical ischemic myocardial infarction as well as ARF that results from I/R injury. Pluripotent MSC, because of their versatility and the ease with which they can be harvested from the bone marrow, culture expanded, and engineered, appear to be a particularly well-suited stem cell type for these clinical indications. [Pg.119]

Yamada, Y, Fujimoto, A., Ito, A., Yoshuni, R., Ueda, M., 2006a. Cluster analysis and gene expression profiles a cDNA microarray system-based comparison between human dental pulp stem cells (hDPSCs) and human mesenchymal stem cells (hMSCs) for tissue engineering ceU therapy. Biomaterials 27, 3766-3781. [Pg.82]

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Cell engineering

Cell therapy

Cell-based therapies

Stem cell therapy

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