Spontaneous abortion pesticides

While the literature abounds with reports of the undesirable reproductive consequences of DDT exposure at all levels of animal systems, little human research in this area has made its way into the open literature. Shepard s Catalog of Teratogenic Agents (ref. 86) and Nisbet-Karch (ref. 47) each list only the work of O Leary et al. (ref. 87), correlating spontaneous abortion in human females with human pesticide residues, and prematurity of human fetuses with DDE levels found in fetal whole blood. Perhaps the more serious risk with DDT and DDE is the significant presence of these two along with other... 

Evidence is similar for humans but limited, and includes male sterility, spontaneous abortions in human females, premature human fetuses, severe neurologic and CNS effects, blood dyscrasias, hepatotoxicity, accumulation of organohalogen pesticides in human lipid tissue—and, perhaps even more important, their presence in human breast milk, whence they can continue to exert influences on growth, development and hormonal, CNS and enzyme systems. Aldrin, dieldrin, chlordane, chlordecone (Kepone), heptachlor epoxide, hexachlorobenzene (HCB) and Mirex are all excreted via breast milk in the human female. This is also true for the related PCBs and PBBs that resist biodecomposition and maintain persistent residence in mammalian tissues. For them, excretion via breast milk may constitute the main—if not sole—elimination route. 

---