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Spider toxin, synthesis

The Fukuyama amine synthesis has seen wide application in the context of natural product synthesis. Complex polyamine natural products that highlight the orthogonal nature of the nosyl protecting group, such as lipogrammistin-A12 and various spider toxins,13 have been efficiently synthesized. This protocol has also been used in the context of medicinal chemistry,14 glucosylamines,15 and blasticidin amino acids.16... [Pg.429]

Sano, M. Nakagawa, K. Yamaguchi, Y Nakajima, T Wakamiya, T. Study on the synthesis and biological activities of fluorescent labeled analogs of spider toxin NPTX-594. Kinki Daigaku Rikogakubu Kenkyu Hokoku 2006,42, 23-28. [Pg.250]

Barslund AF, Poulsen MH, Bach TB, Lucas S, Kristensen AS, Str0mgaard K (2010) Solid-phase synthesis and biological evaluation of Joro spider toxin-4 from Nephila clavata. J Nat Prod 74 483-486... [Pg.210]

Jackson H, Usherwood PN (1988) Spider toxins as tools for dissecting elements of excitatory amino add transmission. Trends Neurosci 11 278-283 Jasys VJ, Kelbaugh PR, Nason DM, PhiUips D, Rosnack KJ, Saccomano NA, Stroh JG, VoUonann RA (1990) Isolation, structure elucidation, and synthesis of novel hydroxylamine-containing polyamines from the venom of the Agelenopsis aperta spider. J Am Chem Soc 112 6696-6704... [Pg.211]

Keywords Ionotropic glutamate receptors Natural products Nicotinic acetylcholine receptors Polyamine toxin Solid-phase synthesis Spider and wasp... [Pg.201]

Chemical Synthesis of Spider and Wasp Polyamine Toxins... [Pg.205]

Lucas S, Poulsen MH, Nprager NG, Barslund AF, Bach TB, Kristensen AS, Str0mgaard K (2012) General synthesis of p-alanine-containing spider polyamine toxins and discovery of Nephila polyamine toxins 1 and 8 as highly potent inhibitors of ionotropic glutamate receptors. J Med Chem 55 10297-10301... [Pg.212]

Str0mgaard K, Jensen LS, Vogensen SB (2005) Polyamine toxins development of selective ligands for ionotropic receptors. Toxicon 45 249-254 Teshima T, Wakamiya T, Aramaki Y, Nakajima T, Kawai N, Shiba T (1987) Synthesis of a new neurotoxin NSTX-3 of Papua New Guinean spider. Tetrahedron Lett 28 3509-3510 Tikhonov DB (2007) Ion channels of glutamate receptors structmal modehng. Mol Membr Biol 24 135-147... [Pg.213]

See other pages where Spider toxin, synthesis is mentioned: [Pg.356]    [Pg.523]    [Pg.524]    [Pg.356]    [Pg.356]    [Pg.605]    [Pg.606]    [Pg.36]    [Pg.236]    [Pg.190]    [Pg.206]    [Pg.211]    [Pg.211]    [Pg.3]    [Pg.198]    [Pg.343]    [Pg.357]    [Pg.524]    [Pg.468]    [Pg.92]    [Pg.1795]    [Pg.606]    [Pg.548]    [Pg.143]    [Pg.205]    [Pg.211]    [Pg.212]    [Pg.214]   


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