Specification inconsistent

While it may appear to be a matter of semantics, the author has become convinced that whether IHC is viewed as a stain or as an assay , can play an important role in establishing the proper mind set of the laboratory staff and the pathologists. The IHC method is regarded by many as simply a stain it produces a visible tinctorial reaction within the tissue section. However, IHC should not be regarded as simply another special stain , like a PAS stain or a silver stain. As already noted, IHC is essentially an ELISA method applied to a tissue section. In this respect, when correctly performed, IHC has the potential to perform as a reproducible and quantitative tissue based ELISA assay much more than a simple stain. That the IHC method mostly does not perform to this level, reflects faults in the application of the method, specifically inconsistent sample preparation, lack of reference or calibration standards, and inadequate validation of reagents (7, 8). The use of RTUs does not finally solve these problems, but for reasons that will be discussed below, can lead to increased reproducibility and consistency in a practical... 

Comparing this with equation (A.2.2), it is seen to predict exactly the same dependence of che effusion rate on pressure and temperature. Furthermore, Che ratio of specific heats y depends relatively weakly on che nature of the gas, through its molecularity, so che prediction chat dV/dt 1/M, which follows from equation (A-2.2) and agrees with Graham s results, is not markedly inconsistent with equation (A.2.3) either. 

The most effective specification is that which accomplishes the desired result with the fewest requirements. Properties and performance should be emphasized rather than how the objectives ate to be achieved. Excessive demonstration of emdition on the part of the writer or failure to recognize the usually considerable processing expertise held by the vendor results in a lengthy and overly detailed document that generally is counterproductive. Redundancy may lead to technical inconsistency. A requirement that cannot be assessed by a prescribed test method or quantitative inspection technique never should be included in the specifications. Wherever possible, tests should be easy to perform and highly correctable with service performance. Tests that indicate service life are especially useful. Standard test references, eg, ASTM methods, ate the most desirable, and those that ate needed should be selected carefully and the numbers of such references should be minimized. To eliminate unnecessary review activity by the would-be complier, the description of a standard test should not be paraphrased or condensed unless the original test is referenced. 

All these items must be properly checked and recorded according to the manufacturer s internal quality checks and formats before they are used in the manufacture of a bus system. This will eliminate any inconsistency in a material or component at the initial stage. Similarly, stage inspections are necessary during the course of manufacturing to ensure quality at every stage and to eliminate incorrect construction and as.sembly or poor workmanship. And thus assure a product of desired specifications and quality. 

It is worthwhile to highlight an inconsistency in the literature. Specifically, one often finds that authors attribute the origins of van der Waals forces solely to dispersion forces. Although this is not strictly correct, in light of the present discussion, one can see that assuming that London and van der Waals forces are synonymous is often not a bad approximation. However, the reader is cautioned that this is not quite correct and can lead to erroneous conclusions under some circumstances. 

Returning to the standard, this clause also only addresses the correction and prevention of nonconformities, i.e. departures from the specified requirements. It does not address the correction of defects, of inconsistencies, of errors, or in fact any deviations from your internal specifications or requirements. As explained in Part 2 Chapter 13, if we apply the definition of nonconformity literally, a departure from a requirement that is not included in the Specified Requirements is not a nonconformity and hence the standard is not requiring corrective action for such deviations. Clearly this was not the intention of the requirement because preventing the recurrence of any problem is a sensible course of action to take, providing it is economical. Economics is, however, the crux of the matter. If you include every requirement in the Specified Requirements , you not only overcomplicate the nonconformity controls but the corrective and preventive action controls as well. 

More pumps fail as a direct result of improper installation than any other single factor. The predominant reasons for these failures include starvation, caused by inadequate or inconsistent suction conditions distortion, caused by pipe strain or improper foundation and turbulent that results from piping or entrained gas problems. Centrifugal pump installation must follow Hydraulic Institute Standards, which provide specific guidelines to prevent these installation and performance problems. This chapter will address the fundamental requirements for proper installation. 

In the second part of the 20th century, the tantalum capacitor industry became a major consumer of tantalum powder. Electrochemically produced tantalum powder, which is characterized by an inconsistent dendrite structure, does not meet the requirements of the tantalum capacitor industry and thus has never been used for this purpose. This is the reason that current production of tantalum powder is performed by sodium reduction of potassium fluorotantalate from molten systems that also contain alkali metal halides. The development of electronics that require smaller sizes and higher capacitances drove the tantalum powder industry to the production of purer and finer powder providing a higher specific charge — CV per gram. This trend initiated the vigorous and rapid development of a sodium reduction process. 

To be effective, this method must be carried out on samples which have been blanched, and upon peas from which the skins have been removed. The heat applied in blanching drives off gases entrapped in the tissues, and removal of the skins is required to remove air that may be entrapped under them, although it materially slows up the operation and makes it very tedious. In order that there may be consistency in grading, the test must be conducted under closely standardized conditions of temperature and solution concentration. This becomes of considerable importance in borderline cases, and failure to take it into consideration no doubt accounts for some of the inconsistency in results experienced by the industry. The test is not a true measure of tenderness, in that it accounts for variation in skin texture only in so far as maturity affects skin texture. Skin texture is affected by factors other than maturity (4). Other methods for the estimation of maturity based upon density or specific gravity have been suggested by Jodidi (16) and by Lee (22). 

The specific surface being a gauge of the fineness of a powder, comparison of the result for M-10 and M-20 in Table 10 shows that the Turbidimeter yielded analyses which were consistent with the burning time data, that is, M-10 is a finer powder than M-20. The Micromero-graph showed a smaller difference between these two lots. The Coulter Counter gave results which were inconsistent with the burning times. It... 

Some aspects of the biochemistry of metabolic processes affecting nutrients appear to have significant consequences for the expected behavior of stable carbon isotopes as tracers of diet. Specifically, we have seen that the simple model of a total scrambling of carbon atoms during endogenous biosynthesis is inconsistent with the expected pathways of some nutrients, whereas other isotopic records in ancient human tissues can be adequately accounted for by this model. 

Whereas the propagation of conditions through the modeling relationships always produces consistent completions in the definition of the initial state, this may not be true with the user-driven specifications. It is possible that a valve specified by the user to be OPEN, is found by the propagation of other conditions to be CLOSED. To detect such potential inconsistencies, we have developed a dependency network (Steele, 1980) to keep track of the flow of computations during constraint propagation. The dependency network is built on the undirected graph that represents the... 

The dimensionless relaxation exponent n is allowed to take the values between 0 and 1. The front factor H0, with the dimension Pa and the characteristic time X0, depends on the specific choice of material. Various values have been assigned in the literature. The spectrum has only two independent parameters, since several constants are lumped into (H0Xo"). For certain materials (the special case of LST), the upper limit of the power law spectrum may diverge to infinity, Xu -> oo, without becoming inconsistent [18]. 

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