Soluble tablets

J. Tsumara, Process for the preparation of water-soluble tablets, U.S. Patent 3.692.896 (1972). 

Use as a first alternative solutions or water soluble tablets. Avoid entero-and depot formulations, and capsules that not can be opened. 

Subcutaneously/IM - Prepare soluble tablets in sterile water and filter through a 0.22 micron membrane filter. 

Soluble tablets for injection - Convulsive states such as those occurring in status epilepticus, tetanus, and strychnine poisoning. 

Bayer first sold aspirin powder to the public in 1899, and introduced a water-soluble tablet in 1900. The company estimates that 50 billion tablets are now consumed yearly on a worldwide basis. In addition to tablets, the French prefer their aspirin in suppository form, while the Italians prefer it fizzy. Aspirin is no longer just taken for headaches and aches and pains. According to Bayer market research, palliation of heart disease is now the number one use of aspirin. 

Aspirin is distributed in water-soluble tablets, cutting the cost of the medication in half. 

Paracetamol is available in liquid, soluble tablet, sachet and melt tablet form. The liquid tends to be the most popular, however this varies between children. There are different brands available and flavour can influence how popular these are. Some products contain additional antihistamines. Note Paracetamol is only indicated for children over three months of age when sold over the counter. 

Sustained-release tablet/capsule Soluble tablets Dispersible tablet... 

Sodium-containing medications and intravenous solutions Soluble tablets containing high levels of sodium Metformin... 

Sediments and Suspensions Sediments may be due to insoluble or sparingly soluble tablet or capsule excipients such as talc, starch, or calcium phosphate, certain poisons such as arsenious oxide, or sometimes to an interaction of the added contaminant with die beverage or drink (e.g. batteiy acid producing a coagulation of protein material). Microscopic examination of the sediment or filtered suspension may give a clue to the nature of die material. 

The analyst should be aware of certain less common preparations which may be encountered. Homoeopathic Preparations. These are usually round, flat/flat tablets witii rough surfaces, 5 to 6 mm in diameter, and contain mainly lactose. Injection Tablets. Small, totally soluble tablets used for making solutions for injection. The most commonly encountered until recently were diamor-phine tablets. These were round, flat/flat tablets, 4 mm in diameter and 2 mm tiiick, weighing 30 mg. They have been discontinued but they may still be seen, having been burgled from pharmacies. These tablets should not be confused with LSD microdots which are usually highly coloured. 

The adverse effects profile of suppositories, soluble tablet formulations, and standard capsules are similar (SEDA-13, 83). A parenteral formulation of piroxicam caused somnolence more often than diclofenac in a doubleblind study, but diclofenac provoked more gastric discomfort and nausea than piroxicam. Local adverse effects of both drugs were pain, burning, and induration at the site of injection (SEDA-15, 103). 

Comments a soluble tablet lubricant. The EINECS number for magnesium lauryl sulfate is 221-450-6. 

Sakr AM, Kassem AA, Farrag NA. The effect of certain disintegrants on water soluble tablets. Manuf Chem Aerosol News 1973 44(1) 37 1. 

Dispersion or soluble tablets The trend toward formulation of dispersible tablets is evident in Europe (184,185) and is becoming more commonplace in the United States with OTC preparations available in the form of the following technologies Zydis ... 

Tsumara J, inventor Process for (he preparation of water-soluble tablets. US patent 3,692, 896. 1972. 

Crivellaro G, Oldani F, inventors Soluble tablet US patent 3,819,824 1974. 

Daunora LG, inventor Water soluble tablet US patent 4,347,235 1982. 

Buccal tablets Effervescent tablets Dispersible tablets Soluble tablets Hard gelatin capsules... 

Soluble tablet Tablet to be dissolved in water prior to administration may or may not be coated... 

Soluble Tablets of Aspirin, B.P, Contain 5 grains of aspirin with citric acid and calcium carbonate. 

Also known as bhara gum, the exudate from the incised trunk of some tropical trees of Terminalia genus (T. bellerica Roxb., T. catappa L., T. randii Baker f.), Combretaceae family, may be used in the formulation of some sustained release pharmaceutical forms famotidine microcapsules (ionic gelation technique) [296] dextromethorphan hydrobromide tablets obtained by direct compression, wet granulation and solid dispersion techniques [297] carvedilol (water insoluble) and theophylline (water soluble) tablets prepared by direct compression - Terminalia gum was assessed as controlled release matrix against xanthan gum and hydroxypropyl methylcellulose [298]. 

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