Soft tissue rheumatism

Rheumatic disease is defined as disease of connective tissue and medical disorders of the musculoskeletal system . The medical discipline concerned with these diseases is referred to as rheumatology. The majority of rheumatic diseases are soft tissue rheumatism and nonspecific low back pain (LBP), autoimmune inflammatory rheumatic diseases, osteoarthritis (OA), osteoporosis, crystal-deposition disease and infectious arthritis. 

Soft tissue rheumatism can be one of the many manifestations of an underlying specific autoimmune disease. Secondary fibromyalgia and enthesitis are the consequences of long-term inadequately treated autoimmune diseases. When no specific underlying causes can be detected, the disorder is called nonspecific soft tissue rheumatism. The major manifestations of soft tissue rheumatism are non-specific... 

LBP, stiff shoulder, epicondylitis and tendonitis. In soft tissue rheumatism pain at rest and/or during activity, stiffness, tenderness, and disability are the predominant features. Physical deformities are minimal but disabilities are major problems. 

Medical non-pharmaceutical therapy of soft tissue rheumatism includes general and local rest, often physiotherapy, occupational therapy, and early mobilization. The pharmaceutical therapy of soft tissue rheumatism comprises analgesics and NSAIDs, the latter when inflammatory components are present. 

Diffusion of salicylate salts from skin into synovial fluid has only been studied in the knee, where the concentrations are too low for significant anti-inflammatory effect. Direct diffusion from skin into the synovial fluid appears insignificant, although these agents may still be effective for soft tissue rheumatism, which is frequently superficial. 

Respiratory, skin, and soft-tissue infections UTIs pelvic inflammatory disease (PID) brucellosis trachoma Rocky Mountain spotted fever typhus Q fever lickettsia severe acne (Adoxa) smallpox psittacosis ornithosis granuloma inguinale lymphogranuloma venereum intestinal amebiasis (adjunctive treatment) prevention of rheumatic fever ... 

Human foods that are particularly rich in copper (20 to 400 mg Cu/kg) include oysters, crustaceans, beef and lamb livers, nuts, dried legumes, dried vine and stone fruits, and cocoa (USEPA 1980). In humans, copper is present in every tissue analyzed (Schroeder et al. 1966). A 70-kg human male usually contains 70 to 120 mg of copper (USEPA 1980). The brain cortex usually contains 18% of the total copper, liver 15%, muscle 33%, and the remainder in other tissues — especially the iris and choroid of the eye. Brain gray matter (cortex) has significantly more copper than white matter (cerebellum) copper tends to increase with increasing age in both cortex and cerebellum. In newborns, liver and spleen contain about 50% of the total body burden of copper (USEPA 1980). Liver copper concentrations were usually elevated in people from areas with soft water (Schroeder et al. 1966). Elevated copper concentrations in human livers are also associated with hepatic disease, tuberculosis, hypertension, pneumonia, senile dementia, rheumatic heart disease, and certain types of cancer (Schroeder et al. 1966). 

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