Slit lamp biomicroscopy

Slit-lamp biomicroscopy (with dilated pupils)... 

A 59-year-old woman who for 20 years had taken chlorpromazine up to 1200 mg/day (mean dose 400 mg/day) gradually developed blurred vision in her left eye. Slit-lamp biomicroscopy showed multiple fine creamy-white deposits on her corneal endothelium and anterior crystalline lens capsule bilaterally. Microstructural analysis of the corneal endothelium showed that there were no abnormalities in cellular morphology resulting from these deposits. 

Patients presenting with a retinal detachment typically report an onset of flashing lights (photopsia) and floaters. Patients may also report decreased peripheral or central vision. Any patient presenting with these symptoms requires prompt dilation and a thorough examination of the central and peripheral retina. Slit-lamp biomicroscopy and indirect ophthalmoscopy with scleral depression are... 

Investigation of those overexposed to screening smokes should include, at least, chest radiograph, pulmonary function tests, arterial oxygen tension measurement, blood clinical chemistry, sputum culture, ophthalmic examination with slit-lamp biomicroscopy, and possibly measurement of intraocular pressure. If available, CT scan may be used to assess the severity of lung injury (Hsu et al., 2005). With some smokes, notably white phosphorus, there may be skin contamination with severe irritation and penetrating bums the management of white phosphoms skin burns is discussed in detail in Section VI.A.2. 

Rengstorff and Mershon (1969) contaminated the eyes of human volunteers with 0.1 or 0.25% CS in water. This resulted in marked blepharospasm persisting for 10 to 135 s and transient conjunctivitis, but no evidence for corneal injury on slit-lamp biomicroscopy. They further examined CS by applying, as drops or spray, 0.1 or 0.25% CS solutions in water and 0.5% polysorbate 20 (Rengstorff and Mershon, 1971). After 1 to 5 s, there was intense eye pain and blepharospasm, the effects being worse with aerosol than with drops. Attenuation of effects began by... 

Repeated exposure of the eye was studied by Rengstorff et al. (1975) who applied 0.025 ml of 5% CR suspension to the eye of rabbits for 5 days a week for 4 weeks, and kept under observation for 60 days. There was transient conjunctivitis, but no corneal effects on slit-lamp biomicroscopy and no fluorescein staining. Light and electron microscopy at 32 days after the final dose did not show any corneal injury. 

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