Skin streaking

Mice are utilized for testing antiseptics for appHcation to cuts, wounds, and incisions (339). The test bacteria, type 1 pneumococcus and hemolytic streptococcus, ate appHed to the taHs of anaesthetized mice. The tip of the taH is then dipped into the antiseptic for 2 min, after which one-half inch of the taH is removed and inserted into the peritoneal cavity and the incision is closed. If after 10 days the animals survive, the product is considered satisfactory for use as a skin antiseptic. The blood of dead animals is sampled and streaked on blood agar for confirmation of infection from the test bacteria as the cause of death. Since lack of toxicity is another requirement of a product to be appHed to wounds, this test has been combined with a toxicity test (340). 

In the nailbed, a black streak or wide variegated brown streak, elevation of nailbed, skin next to nail becomes darker, nail looks deformed or is being destroyed size of nail streak increases over time. 

Of all these formulations, it is the diverse semisolids that stand out as being uniquely topical. Semisolid systems fulfill a special topical need as they cling to the surface of the skin to which they are applied, generally until being washed off or worn off. In contrast, fluid systems have poor substantivity and readily streak and run off the desired area. Similarly, powders have poor staying properties. Importantly, the fundamental physicochemical characteristics of solutions, liquid emulsions and suspensions, and powders are independent of their route of application, and are discussed adequately elsewhere in this text and need not be reconsidered. This is not to say the compositions of such systems cannot be uniquely topical, for there are chemicals that can be safely applied to the... 

Glanders occurs in both acute and chronic forms. The acute form is inhaled and affects the upper respiratory tract. In nature, the acute form kills infected animals in 3 to 4 weeks. The acute form infects the nasal, oral, and conjunctival mucous membranes, causing blood-streaked discharges from the nose along with nodules and ulcerations. The chronic form affects the joints and lymph as multiple skin nodules begin to ulcerate and are filled with pus. Other symptoms include fever, sweats, myalgia, headache, enlarged spleen, and chest pain. Sometimes pneumonia is present. As few as 1 to 10 bacteria delivered to animals by aerosol can be lethal.3... 

But this is only half of the transformation. The blackness of the blackface not only masks Jewish physicality but also unites Jack with Mary by casting the actor s whiteness in stark relief. The film self-consciously plays on the white-and-black contrasts inherent in the minstrel form—as when, in one scene backstage, Jack wipes a white glove across his eyes, leaving a white streak across his face —thus heightening the visual impact of Jolson s white skin.69 The white streaking effect is important to Jakie s overall transformation, but it is especially important to his liaison with... 

Common and immediate side effects of micro-dermabrasion are erythema, which usually subsides within 24 h but may occasionally be prolonged, and a slight burning sensation [13]. Purpura and petechiae may develop, especially on more delicate areas of skin, but these usually resolve spontaneously. Other potential complications are postinflammatory hyperpigmentation and, if excessive pressure is used, streaking marks. One unusual case of a severe urticarial response to miCTodermabrasion has been reported, which may... 

Rayon (left) has a lobed cross section which is typical for fibers spun industrially by the viscose process. In contrast, Lyocell (middle) displays a round shape similar to the cellulose carbamate example (right). (In all the micrographs, the dark streaks are overlaps of sample material caused by the cutting movement of the ultra microtome knife.) Cross sectional shape and pore structure are strongly dependent on the precipitation conditions. For NMMO fibers [11] it was shown that harsh precipitation with water gave dense, round structures while softer precipitation into alcohols lead to a skin-core stmcture with dense skin and a porous inner region. StiU, cross sections are round in contrast to viscose-ty fibers. 

Lymphangitis Symptom of septicemia in which red streaks due to inflamed lymphatics appear beneath the skin. 

Once it touches the skin, urushiol begins to penetrate in a matter of minutes. A reaction will appear as a line or streak of rash. Redness and swelling are followed by bhsters and severe itching. In a few... 

An infection may develop long after the bite. Symptoms of infection include pain tenderness at the wound, redness, heat, swelling, pus at the wound, red streaks in the skin around the wound, and possible swollen glands close to the wound. 

Poison-ivy-like streaks of vesicles and bullae in light-exposed sites can be caused by photocontact dermatitis, and when produced by psoralens, the acute eruption is typically followed by pigmentation There are multiple mechanisms of phytophotodermatitis, but most such reactions are caused by plants containing furanocoumarins or psoralens, including certain members of the Umbelliferae and Rutaceae (citrus) [125]. The sensitizer can be spread with the hands or even thrown onto the skin from a string trimmer [126]. Of course, it is necessary to have adequate UV-A exposure in addition to contact with the plant. 

Two patients are reported (45) who received bleomycin and developed linear streaking of the torso and arms, presenting further support for the concept that local irritational pressure is the triggering event which results in an increase in local blood perfusion, possibly allowing increased quantities of the drug to be delivered to selective skin sites. 

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