Single-dosed powders packaging

Single-dose powders are measured quantities of a solid mass packaged in paper or, in the case of industrially manufactured products, in sachets. Single-dose powders are traditionally prepared for children and elderly because of difficulties in... 

The preparation of the powder mixture is analogous to the preparation of single-dose powders (see Sect. 4.5), but the flow properties are less critical, because the powder mixture does not have to be distributed evenly over dose units. A diluent is generally not necessary, but in case it is required, lactose is often used. Bulk or multidose powders can be packaged in glass, plastic, metal or other containers that have a wide mouth to allow the handling of the powdermeasuring device. 

Single-dose powders are packaged in a suitable powder fold box, a plastic bag with locking clip or, in case of an authorised medicine, in sachets. 

Single dose oral powders are dispensed in powder paper or sachets. For the packaging of single dose powders, paper qualities of 40-120 g/m should be used. Powder paper must not be contaminated, should not shed fibers and there should be minimal variance in weight per area (= constant powder paper weight) within each batch. 

Paper is the primary packaging layer for the packaging of single dose oral powders in powder paper (Sect. 24.4.12). However, it is more common for paper and cardboard to be used as secondary or tertiary packaging layer. Paper is also the basic material of a special packaging material the label (Sect. 24.2.6). 

Single-dose oral powders in powder paper can be packaged in a plastic bag with a clip. Single-dose oral powders can also be packaged in small sealed pouches from a laminate foil material including an aluminium layer. These primary containers are called sachets. Next to the use as primary container, bags are also used as secondary container. 

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