Simon metabolics

Gagnaire F, Simon P, Bonnet P, et al. 1986. The influence of simultaneous exposure to carbon disulfide and hydrogen sulfide on the peripheral nerve toxicity and metabolism of carbon disulfide in rats. Toxicol Lett 34 175-183. 

Louilot, A., Le Moal, M., and Simon, H., Presynaptic control of dopamine metabolism in the nucleus accumbens. Lack of effect of buspirone as demonstrated using in vivo voltammetry, Life Sci., 40, 2017, 1987. 

London, E.D., Simon, S.L., Berman, S.M. et al. Mood disturbances and regional cerebral metabolic abnormalities in recently abstinent methamphetamine abusers. Arch. Gen. Psychiatry. 61 73, 2004. 

B. Wright, W. Simon, and T. Walsh, A kinetic model of metabolism essential to differentiation in Dictyostelium discoideum. Proc. Natl. Acad. Sci. 60, 644 651 (1968). 

Ensley, B. D., Osslund, T. D., Joyce, M. Simon, M.J. (1987). Expression and complementation of naphthalene dioxygenase activity in Escherichia coli. In Microbial Metabolism and the Carbon Cycle, ed. S. R. Hagedorn, R. S. Hanson D. A. Kunz, pp. 437-55. New York Harwood Academic Publishers. 

Fonne-Pfister, R., Simon, A., Salaun, J.P., and Durst, F., Xenobiotic metabolism in higher plants. Involvement of microsomal cytochrome P-450 in aminopyrine N-demethylation, Plant Sci., 55, 9-20, 1988. 

A further consideration is which barbiturate to employ. We recommend the use of barbital because this substance, in contrast to many other barbiturates, undergoes no metabolism (Remmer 1972 Simon et al. 1992). For this reason, results obtained can be more readily interpreted in terms of a pharmacological interaction without confounding by pharmacokinetic or metabolic factors. 

Remmer H (1972) Induction of drug metabolizing enzyme system in the liver. Eur J Clin Pharmacol 5 116-136 Simon P, Chermat R, Doare L et al. (1992) Interactions im-prevues de divers psychotropes avec les effets du barbital et du pentobarbital chez la souris. J Pharmacol 13 241-252... 

Most of the theoretical details of the material covered in this chapter can be found in Coveil et al. (4), Jacquez and Simon (5), and Jacquez (6). Of particular importance to this chapter is the material covered in Coveil et al. (4) in which the relationships between the calculation of kinetic parameters from statistical moments and the same parameters calculated from the rate constants of a linear, constant-coefficient compartmental model are derived. Jacquez and Simon (5) discuss in detail the mathematical properties of systems that depend upon local mass balance this forms the basis for understanding compartmental models and the simplifications that result from certain assumptions about a system under study. Berman (7) gives examples using metabolic turnover data, while the examples provided in Gibaldi and Perrier (8) and Rowland and Tozer (9) are more familiar to clinical phar maco logists. 

Glycolysis produces energy. Michael Johnson sprints to another victory in the 200-meter semifinals of the Olympics. Johnson, like anyone who sprints, requires a source of energy that can be rapidly accessed. The anaerobic metabolism of glucose the process of glycolysis provides such a source of energy for short, intense bouts of exercise. [Simon Bruty/ Allsport.]... 

Funck-Brentano C, Thomas G, Jacqz-Aigrain E, Poirier JM, Simon T, Bereziat G, Jaillon P. Polymorphism of dextromethorphan metabolism relationships between phenotype, genotype and response to the administration of encainide in humans. J Pharmacol Exp Ther 1992 263(2) 780-6. 

Simon D, Senan C, Gamier P, Saint-Paul M, Garat E, Thibult N, Papoz L. Effects of oral contraceptives on carbohydrate and lipid metabolisms in a healthy population the Telecom study. Am J Obstet Gynecol 1990 163(1 Pt 2) 382-7. 

Escudero, E.L., Boerrigter, P.J., Bennink, H.J., Epifanio, R., Horcajadas, J.A., Olivennes, F., Pellicer, A. and Simon, C. (2005) Mifepristone is an effective oral alternative for the prevention of premature luteinizing hormone surges and for premature luteinization in women undergoing controlled ovarian hyperstimulation for in vitro fertilization. Journal of Clinical Endocrinology and Metabolism, 90, 2081-2088... 

Liapakis G, Tallent M, Reisine T (1996c) Molecular and functional properties of somatostatin receptor subtypes. Metabolism 1 12-13 Libert F, Parmentier M, Lefort A, Dinsart C, Wan Sande J, Maenhaut C, Simons M-J, DuMont JE, Vassart G (1989) Selective amplification and cloning of four new members of the G protein-coupled receptor family. Science 244 569-572 Liu YF, Jakobs KH, Rasenick MM, Albert PR (1994) G protein specificity in receptor-effector coupling. Analysis of the roles of Go and Giz in GH4C1 pituitary cells. J Biol Chem 269 13880-13886... 

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