Serum factor influencing

B15. Bodansky, A., Phosphatase studies Determination of serum phosphatase factors influencing the accuracy of the determination. J. Biol. Chem. 101, 93-104 (1933). 

Nondystrophic Factors Influencing Muscle EfBux and Serum Enzyme... 

Nondystbophic Factors Influencing Muscle Efflux AND Serum Enzyme Activity... 

Cox, D. W., Factors Influencing Serum Ceruloplasmin Levels in Normal... 

Many factors influence serum iron concentration and TIBC. Changes that may be observed in various physiological or pathological conditions are listed in Table 31-4. Day-to-day variation is quite notable in healthy people. A distinct diurnal variation results in serum iron concentrations being lower in the afternoon than morning and quite low in the evening (as low as 10 to 20 j,g/dL [2 to 4 imol/L] in healthy people). Because of the numerous causes of low serum iron concentration, results must be interpreted with caution. Furthermore, many people with mild iron deficiency have normal values for serum iron concentration and TIBC. 

Accuracy of colorimetric measurements. An accuracy of 0.06-0.1 pH unit is possible in routine work when buffer solutions differing by 0.2 pH are employed. Estimates to 0.01 unit, as is customary when measuring the pH of blood serum, are significant only if the pH difference between comparison solutions is 0.05-0.1 pH unit. The attainment of such precision is facilitated by the colorimeter or spectrophotometer, although an experienced worker may obtain equal precision with the naked eye. In no event should the accuracy of the measurement be exaggerated, for a number of other factors influence the results (differences in ionic strengths of unknown solution and buffer). An accuracy... 

La Du, B., N., Human serum paraoxonase/arylesterase. In Kalow, W., Ed., Genetic Factors Influencing the Metabolism of Foreign Compounds International Encyclopedia of Pharmacology and Therapeutics, Pergamon Press, New York, 51-91,1992. 

In this connection one must point out the importance of multi-element analysis in serum for diagnostic purposes. The determination of a singie trace eiement gives no evidence about the relative abundance of this element, because many factors influence the "normal" actual trace element status stress situations, nutrition etc. The trace elements are mostly bound to proteins and therefore it should be standardized to the total protein content (Fig. 16). In practice, the phosphorus concentration in serum is a sufficient... 

Shaw, L. M., Fields, L., and Mayock, R., Factors influencing theophylline serum protein binding, Clin. Pharmacol. Ther, 32(4) 490 96, 1982. 

The mechanism of the insulin antagonism induced by growth hormone and corticosteroids is unknown. Since the hormone has not in general been found to induce insulin antagonism in muscle in vitro, attempts have been made to identify an active principle in serum responsible for the antiinsulin effect of the hormone in vivo. Evidence has been obtained for the presence of such a factor in the serum of rats (Bornstein and Park 1953) and cats (Vallance Owen and Lukens, 1957), but the physiological significance of these and other serum factors with an influence on the metabolism of glucose by muscle is by no means certain at the present time. Hardwick et al. (1959) have found that the retention of insulin-/ by forearm tissues... 

Y3 Yngner, T., Lewan, L. and Petersen, I. Factors influencing the serum activity in mice after intravenous and intraperi-toneal injection of [ C] orotic acid. Experientia, 31, 387-388 (1975)... 

Johansson, S. G. O., Bennich, H., Berg, T., and Hogman, C., 1970, Some factors influencing the serum IgE levels in atopic diseases, Clin. Exp. Immunol. 6 43. 

B. Poutrel, J. P. Caffin, P. Rainard. Physiological and pathological factors influencing bovine serum albumin content of milk. J Dairy Sci 66 535, 1983. 

The level of the calcium in blood is largely maintained by the action of the parathyroid glands which are stimulated to hypersecretion of their hormone by low serum levels and generally to hyposecretion by high levels, the effect being to bring about a return of calcium concentration to normal. The actions of this and other factors influencing blood calcium are discussed later in this chapter. 

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