Separator column acetic acid

In a process for the manufacture of acetone, acetone is separated from acetic acid by distillation. The feed to the column is 60 mol per cent acetone, the balance acetic acid. 

Conventionally peracetic acid is produced in a tank reactor in the presence of homogeneous acid catalyst. In the process, sulfuric acid catalyst is first charged into the reactor, after which acetic acid and hydrogen peroxide are fed into the reactor. The mixture is heated up and equilibrium reaction (1) takes place. When homogeneous acid catalyst is used, separation of it from equilibrium mixture is carried out in a distillation column. When equilibrium is reached, sub-atmospheric pressure is drawn in the reactor. Vaporization of the reaction mixture begins. In the distillation column acetic acid, hydrogen peroxide and peracetic acid are separated from sulphuric acid catalyst (Swem, D., 1970). The simplified scheme of the conventional process is illustrated in Figure 3. 

Also in this process, the esteriheation reaction and the separation of the products take place in the same equipment the distillation column. Acetic acid and ethanol react to produce ethyl acetate and water ... 

Usually extraction implies distillation, because of solvent recycling. Fig. 7.29 displays a typical application, the separation of acetic acid from an aqueous solution with isopropyl-ether. After extraction, the organic phase is sent to the column C-I where the acetic acid is recovered as bottoms. The distillate separates in two phases in decanter. The organic phase is sent back to C-1 as reflux and as solvent to the extractor, while the water-rich phase goes to the second column C-2. The raffinate from the extraction column is sent to C-2, from which wastewater is recovered in bottom, while the solvent separating in top is sent to the decanter of C-1 and recycled to the extraction unit. 

Crude vinyl acetate is separated from acetic acid and water in an azeotropic distillation system. Acetic acid is recycled to the acetic acid vaporizer and the vinyl acetate product is separated from other by-products in a two-column recovery section. Light ends are removed in the first column followed by a heavy ends in the final column. The light ends, primarily methyl acetate, and the heavy ends, mostly ethyl acetate and acetaldehyde, are incinerated. The vinyl acetate product from the overhead of the heavy ends column is cooled and sent to storage. 

The concentrations of benzoic acid, aspartame, caffeine, and saccharin in a variety of beverages are determined in this experiment. A Gig column and a mobile phase of 80% v/v acetic acid (pH = 4.2) and 20% v/v methanol are used to effect the separation. A UV detector set to 254 nm is used to measure the eluent s absorbance. The ability to adjust retention times by changing the mobile phase s pH is also explored. 

This experiment describes the quantitative analysis of the asthma medication Quadrinal for the active ingredients theophylline, salicylic acid, phenobarbital, ephedrine HGl, and potassium iodide. Separations are carried out using a Gi8 column with a mobile phase of 19% v/v acetonitrile, 80% v/v water, and 1% acetic acid. A small amount of triethylamine (0.03% v/v) is included to ensure the elution of ephedrine HGl. A UV detector set to 254 nm is used to record the chromatogram. 

The preliminary precipitation of proteins from milk is realized through the addition of solutions of acetic acid (1,7 mol/1) and sodium acetate (lmol/1) at t = 40-45°C before chromatographic isolation of OxTC. The precipitated proteins are separated by filtration. OxTC is detenuined in filtrate after its isolation on chromatographic column. Contents of OxTC was determined on calibration curve which is linear within concentration range 0,01-1,0 p.g/ml. 

Separated from retinol by column chromatography on water-deactivated alumina with hexane containing a very small percentage of acetone. Also chromatographed on TLC silica gel G, using pet ether/isopropyl ether/acetic acid/water (180 20 2 5) or pet ether/acetonitrile/acetic acid/water (190 10 1 15) to develop the chromatogram. Then recrystd from propylene at low temperature. 

Fig. 7-9. Separation of amino acids after derivatization 5 with OPA and mercaptoethanol. Column Superspher 100 RP-18 (4 pm) LiChroCART 250-4, mobile phase 50 mM sodium acetate buffer pH 7.0/methanol, flowrate 1.0 ml min temperature 40 °C detection fluorescence, excitation 340 nm/emission 445 nm. Sample amino acid standard sample (Merck KGaA Application note W219180).

After an initial distillation to split the coproducts phenol and acetone, each is purified in separate distillation and treating trains. An acetone finishing column distills product acetone from an acetone/water/oil mixture. The oil, which is mostly unreacted cumene, is sent to cumene recovery. Acidic impurities, such as acetic acid and phenol, are neutralized hy caustic injection. Figure 10-7 is a simplified flow diagram of an acetone finishing column, and Table 10-1 shows the feed composition to the acetone finishing column. 

Butylcyclohexanol has been prepared from />-/-butylphenol by reduction under a variety of conditions.3 4 Winstein and Holness5 prepared the pure trans alcohol from the commercial alcohol by repeated crystallization of the acid phthalate followed by saponification of the pure trans ester. Eliel and Ro 6 obtained 4-f-butylcyclohexanol containing 91% of the trans isomer by lithium aluminum hydride reduction of the ketone. Iliickel and Kurz 7 reduced />-/-butylphenol with platinum oxide in acetic acid and then separated the isomers by column chromatography. 

ODS3 is a "bulk type" reverse phase (the meaning of which will be discussed later) which has a fairly high capacity and is reasonably stable to small changes in pH. The column was 25 cm long, 4.6 mm in diameter and the mobile phase a methanol water mixture containing acetic acid. In this particular separation the solvent mixture was programmed, a development procedure which will also be discussed in a later chapter. 

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