Selection Functions

The selection function is used to choo.se chromosomes which can then mate and thus give their coded information to the next generation. The idea behind the selection mechanism is to obtain more copies of better chromosomes in the next generation. 

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The characteristic separation curve can be deterrnined for any size separation device by sampling the feed, and coarse and fine streams during steady-state operation. A protocol for determining such selectivity functions has been pubHshed (4). This type of testing, when properly conducted, provides the relationships among d K, and a at operating conditions. These three parameters completely describe a size separation device and can be used to predict the size distribution of the fine and coarse streams. 

C = classifier selectivity matrix, which has classifier selectivity-function values T on diagonal zeros elsewhere... 

Free-radical bromination is an important method of selective functionalization of hydrocarbons. The process is a chain reaction involving the following steps ... 

SELECTIVE FUNCTIONALIZATION OF THE ANGULAR METHYL GROUP AND FURTHER TRANSFORMATION TO 19-NORSTEROIDS... 

Selected Functional Groups and Representative Organic Compounds [58]... 

Select Function) offers the choice among the above-mentioned functions and a user-defined one. (See Algebraic Function .)... 

Functionalized copolymers from dienes and p-alkylstyrenes can serve as dispersants and viscosity index improvers. The functionalities are introduced via the aromatic units [233,234]. The polymers are selectively hydrogenated to produce polymers that have highly controlled amounts of unsaturation, permitting a highly selective functionalization. The dispersant substances may also include a carrier fluid to provide concentrates of the dispersant. 

Generally, all of the assays used for characterization of hits in terms of potency, selectivity, function, and or cellular activity will continue to be used to characterize new compounds synthesized to identify leads. However, additional assays will normally be added to characterize compound selectivity more fully, to provide additional evidence that compounds are acting on the desired pathway and by the desired mechanism. 

The direct use of dioxygen in the catalytic oxidation of nonactivated C-H bonds under mild conditions without using a coreductant was reported by using a K2Pt04/CuCl2 catalytic system to give the selective functionalization of a-amino acids in water.10 The aqueous medium avoided the need for protection of functional groups (Eq. 2.3). 

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