Secretion mechanisms and

Proc. Symp., Gastric Secretion, Mechanisms and Control, T. K. Shnltka, J. A. L. Gilbert and R. C. Harrison, Eds., Pergamon Press, Oxford, 1967. 

The cytosolic forms show no sequence homology to the secreted forms and have a different catalytic mechanism [1]. They are widely distributed and occur... 

There is evidence that protease inhibitors selectively regulate the activity of specific digestive enzymes at the level of gene expression (Rosewicz et al., 1989). Specifically, soybean trypsin inhibitor increases secretion of proteases, including a form of trypsin that is resistant to inhibition but does not cause an increase in amylase secretion. Although the relationships between protease inhibitors and exocrine pancreatic secretion have received the most attention, pancreatic secretion is increased when potato fiber is added to the diet (Jacob et al., 2000), although the mechanism and signaling pathway have not been elucidated. 

The gastrointestinal tract (GIT) is a highly specialized region of the body whose primary functions involve the processes of secretion, digestion, and absorption. Since all nutrients needed by the body, with the exception of oxygen, must first be ingested orally, processed by the GIT, and then made available for absorption into the bloodstream, the GIT represents a significant barrier and interface with the environment. The primary defense mechanisms employed by the gut... 

As demonstrated above, the uptake of [1-C at the apical membrane of differentiated Caco-2 cells occurs via a saturable, facilitated mechanism and is inhibited by Ezetimibe, a clinically used inhibitor of cholesterol absorption. Carotenoids secreted at the basolateral membrane were associated... 

Hydrogen ion secretion. Hydrogen ions are secreted in the proximal tubule, distal tubule, and collecting duct. The secretion of hydrogen ions is an important mechanism in acid-base balance. The normal pH of the arterial blood is 7.4. When the plasma becomes acidic, H+ ion secretion increases and when it becomes alkalotic, H+-ion secretion is reduced. 

CNTs show sign of toxicity. Although biomolecules functionalized CNTs can be cleaned from blood circulation system by renal secretion, so far the course of CNTs metabolism in cells or environment, and the potential measurements to reduce CNTs toxicity, is still not clear. How to clarity those mechanisms and reduced risk measurements associated with CNTs toxicity is a great challenge. 

D. J. Chadwick and J. A. Goode, eds., Mechanisms and Biological Significance of Pulsatile Hormone Secretion. Novartis Foundation Symposium 227, John Wiley Sons, Chichester, UK, 2000. 

Hepatocytes make up 60-70% of the total number of liver cells. They have a well-organized intracellular structure with huge numbers of cell organelles to maintain the high metabolic profile. At the apical side or canalicular membrane the cell is specialized for the secretion of bile components. There are several ATP-dependent transport carriers located on this side of the membrane, which transport bile salts, lipids and xenobiotics into the canaliculus. On the sinusoidal side, the cells specialize in uptake and secretion of a wide variety of components. To increase the surface of the membrane for this exchange with the bloodstream, the sinusoidal domain of the membrane is equipped with irregular microvilli. The microvilli are embedded into the fluid and matrix components of the space of Disse and are in close contact with the sinusoidal blood because of the discontinuous and fenestrated SECs. To facilitate its metabolic functions numerous membrane transport mechanisms and receptors are situated in the membrane. 

Mechanism of Action A mineralocorticoid that acts at distal tubules. Therapeutic Effect Increases potassium and hydrogen ion excretion. Replaces sodium loss and raises blood pressure (with low dosages). Inhibits endogenous adrenal cortical secretion, thymicactivity, and secretion ot corticotropin by pituitary gland (wit h higher dosages). 

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