Screening Double contrast barium enema

Winawer SJ, Stewart ET, Zauber AG et al (2000) A comparison of colonoscopy and double-contrast barium enema for surveillance after polypectomy. National Polyp Study Work Group. N Engl J Med 15 342 1766-1772 Winawer SJ, Fletcher RH, Rex D et al (2003) Colorectal screening and surveillance clinical guidelines rationale-update based on new evidence Gastroenterology 124 544-560... 

Evidence-based comparisons with existing approved screening tests (FOBT, flexible sigmoidoscopy, double contrast barium enema, colonoscopy) will show that none is perfect and that CTC has a sufficient number of benefits and unique attractions to make it a legitimate addition. 

Several studies have shown that patients acceptance of CTC is greater than conventional colonoscopy or double contrast barium enema (Taylor et al. 2003). Development of minimal bowel prep or prep-less CTC through fecal tagging and electronic cleansing appears to be within reach, thus making a truly prep-less colorectal screening test an attractive possibility (Lefere et al. 2002). 

Johnson C, MacCarty R, Welch T et al. (2004) Comparison of the relative sensitivity of CT colonography and double-contrast barium enema for the screen detection of colorectal polyps. Clin Gastroenterol Hepatol 2 314-321 Kusama T, Ota K (2002) Radiological protection for diagnostic examination of pregnant women. Congenital Anomalies 42 10-14... 

Gluecker T, Johnson D, Harmsen W et al. (2003) Colorectal cancer screening with CT colonography, colonoscopy, and double contrast barium enema examination prospective assessment of patient perceptions and preferences. Radiology 227 378-384... 

Yet, there is low public acceptability of screening for colorectal cancer by colonoscopy, and a higher rate of patient compliance can be expected with CT colonoscopy (Gluecker et aL 2003), although the patient must undergo a colonic preparation, as with double-contrast barium enema or colonoscopy. Besides, if polyps or tumors are diagnosed by CT, conventional colonoscopy is required to verify the diagnosis, to obtain a biopsy sample, and to remove them. 

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