Scopolamine butylbromide

Manfio JL, Dos Santos MB, Favreto WAJ, Hoffmann FI, Mertin AC (2009) Validation of a liquid chromatographic/tandem mass spectrometric method for the determination of scopolamine butylbromide in human plasma application of the method to a bioequivalence study. JAOACInt 92 1366-1372... 

This patient participated in a 200-m relay race at an athletics meeting on October 10. After dinner, a dull pain in his left flank occurred and gradually worsened, but it differed from colic. There was no decrease in urine volume or dark urine. At 2330 hours, the patient attended the Emergency Outpatient Unit of our hospital because of the pain. An intramuscular injection of scopolamine butylbromide relieved the... 

Synonyms. Butylscopolamonii Bromidum Hyoscine-A-Butyl Bromide Scopolamine Butylbromide. 

Schiff s bases in gas chromatography, 188 Schiff s Reagent, 144 Schoenocuulon officinale, 1061 Scolaban, 409 Scoline, 998 Scoparium, 972 Scopolamine, 674 Scopolamine bromhydrate, 674 Scopolamine butylbromide, 675 Scopolamine hydrobromide, 674 Scopolamine methylbromide, 675... 

Distension of the gastric wall by ingestion of 600-1000 ml of water is required prior to MR examination of the stomach. Patients are examined in the supine or prone position depending on the location of the gastric lesion. MR imaging is usually performed with a 1.5-T magnet 20-40 mg of scopolamine butylbromide or 1 mg of glucagon is administered intravenously before the examination in order to minimize peristalsis. 

Scopolamine (hyoscine N-butylbromide) is available as an antispasmodic product (20 mg ampule for injection and 20 mg tablets) for use in humans. In addition, there is a veterinary product that contains scopolamine and dipyrone approved for use as an antispasmodic/analgesic in animals. In addition to blocking the effects of acetylcholine at the muscarinic receptor, scopolamine affects nicotinic receptors in intestinal ganglia and does not affect the CNS. In horses, scopolamine is used as an antispasmodic and to relax the rectum to facilitate abdominal palpation. In one report, 0.2 mg/kg was as effective as 0.2 mg/kg scopolamine plus 2.5 mg/kg dipyrone in relieving discomfort caused by balloon dilatation of the cecum (Roelvink et al 1991). The analgesic effect tasted for 20 min. 

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