Schoenocaulon officinale

Quassia amara (Quassia) Schoenocaulon officinale (Sabadilla)... 

Neurotoxin that preferentially binds to activated sodium channels and increases the intracellular calcium concentration. It prolongs the action potential duration in the heart. It is obtained from sabadilla seeds (Schoenocaulon officinale). Yellowish-white amorphous powder that retains water and melts at 356°F. It is insoluble in water but slightly soluble in ether. Various salts (solids) have been reported. The nitrate is sparingly soluble in water. 

Veratrum album L. and Schoenocaulon officinale (Lindl.), Liliaceae, Ang. 

Cevine ( Cevedine) Schoenocaulon officinale Haemolytic derives from... 

A mixture of alkaloids from sabadilla, the dried ripe seeds of Schoenocaulon officinale (Liliaceae). 

Like nieotine and ryania, sabadilla owes its insecticidal powers to several poisonous alkaloids. It is made from the seeds of Schoenocaulon officinale, a lilylike plant found in Venezuela. 

IV) ANTIARRHYTHMIC. It is a SMOOTH MUSCLE RELAXANT and coronary VASODILATOR. It can be used as an antihypertensive and antianginal. and in antimigraine prophylaxis, verapamil hydrochloride verapamil, veratridine is an alkaloid from Schoenocaulon officinale (Liliaceae), and is a neurotoxin and sodium-Channel ACTIVATOR that binds to Na -channels, leading to depolarization. It has similar but weaker actions to batrachotoxin. Vercyte pipobroman. 

The natural insecticide Sabadilla, which is popular with organic farmers, contains 30 alkaloids present at a level of 3-6% in the seeds of Schoenocaulon officinale.235 It can affect the cardiovascular system, respiration, nerve fibers, and skeletal muscles of humans. Gastrointestinal symptoms and hypotension may also result from its ingestion. 

Veratrum alkaloids are produced by lilaceous plants of the suborder Melanthaceae of which Veratrum album, the hellebore of Europe and northern Asia, Veratrum viride, the swamp hellebore or Indian poke of North America, and Schoenocaulon officinale of Central and South America are the best known. The latter yields the sabadilla seed which was used as an insecticide by Indians in pre-Columbian times (Crosby 1971). The alkaloid fraction of the seeds, often termed veratrine, is a poorly defined mixture mostly of the ester alkaloids, veratridine, and cevadine and of the alkamine veracevine or its isomer cevine. 

Sabadilla is the dry, ripe seed of the plant Schoenocaulon officinale, native in the mountains of Mid-America, of the family Liliaceae. Its insecticidal effect has been known since the sixteenth century, but its study by scientific methods began only in 1938 (Allen et ai, 1944). 

Veratruie (Mixture), This veratrine is a mixture of the alkaloids cevadine, veratridine. cevadilline, sabadine, cevine from seeds of Schoenocaulon officinale (Schlecht. Cham.) A. Gray, LUiaceae. 

OCCURRENCE. Cevadine, C32H49O9N, which has also been described under the names veratrine and crystalline veratrine, was early recognized as the most abundant alkaloid of Sabadilla seeds, Veratrum sabadilla Retz. (Schoenocaulon officinale A. Gray). It was described by Merck... 

Veracevine (protocevine) C27H43NO8 509.64 220-225 -26° (C2H5OH) Schoenocaulon officinale 5876-23-3... 

Kanchanapoom T, Suga K, Kasai R, Yamasaki K, Kamel MS, Mohamed MH (2002) Stilbene and 2-arylbenzofuran glucosides from the rhizomes of Schoenocaulon officinale. Chem Pharm Bull 50 863-865... 

This group of alkaloids is obtained from three Liliaceous plants, sabadilla or cevadilla seeds (Schoenocaulon officinale, A. Gray) and the rhizomes of... 

Known for centuries as a louse powder is saba-dilla (Syn. cevadilla, caustic barley) derived from the ground seeds of Schoenocaulon officinale (Li-liaceae). The active compounds are two alkoloids cevadlne [62-59-9] and veratridine [71-62-5], They are used in thrips Thysanoptem) control in sugar beet. 

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