Saussurea radix

Dehydrocostus lactone (249), inhibitors of nitric oxide synthases and TNF-a, isolated from Saussurea radix, was incubated with C. echinulata to afford (+) lla,13 diltydrodel drocostuslactone (250a). The epoxide (251) and a Cll reduced compound (250) were obtained by the aforementioned microorganisms (Galal, 2001). 

Costunolide (165), a very unstable sesquiterpene y-lactone, from Saussurea radix, was treated in Aspergillus niger to produce three dihydrocostunolides (166-168) (Clark and Hufford, 1979). Costunolide is easily converted into eudesmanolides (169-172) in diluted acid, thus 166-168 might be biotransformed after being cyclized in the medium including the microorganisms. If the crude... 

Yamahara J, Kobayashi M, Miki K, Kozuka M et al. 1985 Cholagogic and antiulcer effect of Saussureae radix and its active components. Chem Pharm Bull 33 1285-1288... 

For the initial stage of dysentery, subtract Ginseng and add Radix Saussureae Seu Vladimiriae Mu Xiang) and Rhizoma Coptidis Chinensis Huang Lian). 

For severe bloating, add Radix Saussureae Seu Vladimiriae (Mu Xiang) and Semen Arecae Catechu (Bing Lang). 

For cold hernia pain due to cold and dampness attacking the small intestine, subtract Peony, Mint, and Bupleurum and add Fructus Meliae Toosendan Chuan Lian Zi), Fructus Evodiae Rutecarpae Wu Zhu Yu), Radix Saussureae Seu Vladimiriae Mu Xiang), and Fructus Foeniculi Vulgaris Xiao Hui Xiang). 

For severe abdominal pain and tenesmus, add Radix Saussureae Seu Vladimiriae (Mu Xiang), Fructus Citri Seu Ponciri (Zhi Ke), Radix Albus Paeoniae Lactiflorae (Bai Shao), and Radix Angelicae Sinensis (Dang Gui). 

For bacillary dysentery, add Radix Sanguisorbae Di Yu), Herba Agrimoniae Pilosae Xian He Cad), and Radix Saussureae Seu Vladimiriae Mu Xiang). 

For summerheat pattern with diarrhea, add Radix Puerariae Lobatae (Ge Gen), Herba Agastachis Seu Pogostemi (Huo Xiang), and Radix Saussureae Seu Vladimiriae (Mu Xiang). This results in Qian Shi Bai Zhu San (Master Qian s Atractylodis Powder). 

For menopausal diarrhea caused by emotional upset in turn due to liver qi invading the spleen, add Radix Dioscoreae Oppositae (Shan Yao), Rhizoma Atractylodis Macrocephalae (Bai Zhu), Radix Saussureae Seu Vladimiriae Mu Xiang), Fructus Zizyphi Jujubae Da Zao), and mix-fried Radix Glycyrrhizae Zhi Gan Gao). 

For vomiting due to stomach cold, add Radix Saussureae Seu Vladimiriae (Mu Xiang) and Fructus Amomi (Sha Ren). This results in Xiang Sha Er Chen Tang (Saussurea Amomum Two Aged [Ingredients]... 

For abdominal pain and distention, add Fructus Amomi (ShaReri) and Radix Saussureae Seu Vladimiriae (Mu... 

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