Salicylates interaction

Ramanathan M. Warfarin—topical salicylate interactions case reports. Med J Malaysia 1995 50(3) 278-9. 

Rousseau P, Fuentevilla-Clifton A. Acetazolamide and salicylate interaction in the elderly a case report JAm GeriatrSoc (1993) 41, 868-9. 

Koren G, Roifman C, Gelfand E, Lavi S, Suria D, Stein L. Corticosteroids-salicylate interaction in a case of juvenile rheumatoid artiiritis. Ther Drug Monit ( 9 T) 9,177—9. 

Leonard RL, Knott PJ, Rankin GO, Robinson DS, Melnick DE. Phenytoin-salicylate interaction. Clin Pharmacol Ther (1981) 29, 56-60. 

Inoue F, Walsh RJ. Folate supplements and phenytoin-salicylate interaction. Neurology (1983) 33, 115-16. 

Salicyl-u-toluide has been prepared only by the action of phosphorus oxychloride upon a mixture of salicylic acid and o-toluidine. The useful methods of preparation of salicylanilide are by the interaction of salicylic acid and aniline in the presence of phosphorus trichloride, by heating phenyl salicylate and aniline, and from o-hydroxybenzamide and bromobenzene in the presence of small amounts of sodium acetate and metallic copper. A number of these and other anilides have been described. ... 

Discuss the types, uses, general drug actions, common adverse reactions, contraindications, precautions, and interactions of the salicylates and acetaminophen. 

As the solvent mixture also contained 225 mg of tetramethyl ammonium hydroxide pentahydrate per liter at a high water content (75%), the surface of the reverse phase would have been largely covered with the tetramethyl ammonium hydroxide pentahydrate. This would have acted as an adsorbed ion exchange stationary phase. It is clear that the free acids, salicylic acid, acetylsalicylic acid (aspirin) and benzoic acid were retained largely by ionic interactions with adsorbed basic ion exchanger and partly by dispersive interactions with the exposed reversed phase. The acetaminophen and the caffeine, on the other hand, being unionized substances, were retained only by dispersive interactions with the exposed reversed phase. 

The interactions between the chiral Schiff bases being derivatives of 2-aminoalcohols and substituted salicylic aldehydes and titanium (IV) isopropoxide [33] have been monitored by aH NMR spectroscopy.81... 

The possibility of carrying out a multistep synthesis makes it possible to obtain P,B-containing derivatives from unstable intermediate a-hydroxyalkylphosphines. Thus, phenylphosphine, salicylic aldehyde, phenylboric acid anhydride, and triethylamine interact to give a bicyc-lic product—2,8,9-trioxa-1 -borata-4-phospha-6,7 -benzobicyclo [3,3,3] nonane (115) [Eq. (74)] (87IZV2118 89IZV946). In this case an aldehyde takes part in the reaction opening up new synthetic possibilities. 

More significant differences from the properties of cyclic boryloxyalkyl-phosphines were revealed for 5,6-benzo-4-diphenylphosphino-2-phenyl-l,3-dioxa-2-boracyclohexane (126), obtained by the interaction of diphe-nylphosphine, salicylic aldehyde, and phenylboric acid ester [Eq. (83)] (92IZV196). 

The interaction of ligands derived from salicylic acid and its derivatives has been extensively investigated (83, 147, 149, 160, 170, 176, 183-205). A similar situation obtains with regard to l-hydroxy-2-naphthoic acid (185, 194, 196, 198, 206-215). Salicylic acid derivatives may be useful in chelation therapy for beryllium poisoning (2). 

Phosphine complexes, osmium, 19 642 Phosphine coordination complexes, of uranium, 25 436 Phosphine derivatives, 19 28 Phosphine oxide(s), 11 495-496 19 66 predicted deviations from Raoult s law based on hydrogen-bonding interactions, 8 814t in salicylic acid manufacture, 22 8 Phosphine oxide diols/triols, 11 501 Phosphine selenides, 22 90 Phosphinic acid, 19 20, 54-55 Phosphinic anhydride, 11 499 Phosphinothricin acetyltransferase (PAT) proteins, 13 360 Phosphite esters, 19 20 Phosphites, in VDC polymer stabilization, 25 720... 

Phytohormones such as ethylene, salicylic acid (SA), JA, and abscisic acid (ABA) regulate responses of plants to stresses via action referred as signaling crosstalk. Moreover, reactive oxygen species (ROS), the toxic byproducts of aerobic metabolism, play the important role of signaling molecules. Usually, the defensive responses of plants depend on the interaction (positive or negative) between phytohormone signaling pathways rather than on the independent contribution of each of them. " ... 

A similar example of curing inhibition In an acidic medium has been observed when moderate amounts of salicylic acid were added to epoxy-amine matrix systems. (26) Such behavior may beresponsible for the poor bond strengths observed with the NTMP-containing oxide-primer specimens. In environments containing an aggressive species (e.g.. Cl ), the anion may interact with and become incorporated into the NTMP-oxide matrix, whereby it can attack the metal surface. 

Certainly of genuine origin is anachelin, a strange compound whose biosynthesis requires inter alia steps from the peptide and polyketide paths. It exists in an open (anachelin H, Fig. 3, (10)) and two cyclic forms arising from an interaction of the carbonyl group of the salicylic acid residue with one of the neighboring... 

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