S Proteasome

Guerrero C, Tagwerker C, Kaiser P, et al. An integrated mass spectrometry-based proteomic approach quantitative analysis of tandem affinity-purified in vivo cross-linked protein complexes (QTAX) to decipher the 26 S proteasome-interacting network. Mol. Cell. Proteomics. 2006 5 366-378. 

Guerrero et al. (2006) used this technique along with the quantitative mass spec strategy called SILAC (stable isotope labeling of amino acids in cell culture Ong et al., 2002) to identify the yeast proteins that interact with the 26 S proteasome. 

Baboshina, O. V. and Haas, A. L. Novel multiubiquitin chain linkages catalyzed by the conjugating enzymes E2EPF and RAD6 are recognized by 26 S proteasome subunit 5, J Biol Chem, 1996, 271, 2823-31. 

Kessel, M. et al. Homology in structural organization between E. coli ClpAP protease the eukaryotic 26 S proteasome. J Mol Biol 1995, 250, 587-594. 

Haetmann-Peteesen, R., Tanaka, K., and Hendil, K. B. Quaternary structure of the ATPase complex of human 26 S proteasomes determined by chemical cross-linking. Arch Biochem Biophys 2001, 386, 89-94. 

Kajava, a. V. What curves alpha-solenoids Fvidence for an alpha-helical toroid structure of Rpnl and Rpn2 proteins of the 26 S proteasome. J Biol Chem 2002, 277, 49791-8. 

Coen, P. G., McDonald, E. R., 3rd, Herman, J. G., and El-Deiey, W. S. Tat-binding protein-1, a component of the 26 S proteasome, contributes to the E3 ubiquitin ligase function of the von Hippel-Lindau protein. Nat Genet... 

Murakami, Y., Matsueuji, S., Hayashi, S. I., Tanahashi, N., and Tanaka, K. ATP-Dependent inactivation and sequestration of ornithine decarboxylase by the 26 S proteasome are prerequisites for degradation. Mol Cell Biol 1999, 39, 7216-27. 

WojciK, C. and DeMartino, G. N. Analysis of Drosophila 26 S proteasome using RNA interference. J Biol Chem 2002, 277, 6188-97. 

Karpov, V., Vetter, I., and Eeldmann, H. Rpn4p acts as a transcription factor by binding to PACE, a nonamer box found upstream of 26 S proteasomal and other genes in yeast. FEBS Lett 1999, 450, 27-34. 

Tone, Y. and Ton, E. A. Noblp is required for biogenesis of the 26 S proteasome and degraded upon its maturation in Saccharomyces cere-visiae. Genes Dev 2002, 16, 3142—57. 

P., and Goldberg, A. L. An archaebacterial ATPase, homologous to ATPases in the eukaryotic 26 S proteasome, activates protein breakdown by 20 S proteasomes. J. Biol. Chem. 1999, 274, 26008-26014. 

Rasmussen, T. P., Culbertson, M. R., and Hochsteasser, M. The yeast SEN3 gene encodes a regulatory subunit of the 26 S proteasome complex required for ubiquitin-dependent protein degradation in vivo. Mol. Cell. Biol. 1995, 35, 6311-6321. 

Fu, H., Sadis, S., Rubin, D. M., Glickman, M., van Nocker, S., Finley, D., and Vierstra, R. D. Multiubiquitin chain binding and protein degradation are mediated by distinct domains within the 26 S proteasome subunit Mcbl./. Biol. Chem. 1998, 273, 1970-1981. 

J. R., and Deshaies, R. J. Selective degradation of ubiquitinated Sid by purified 26 S proteasome yields active... 

Saeki, Y., Sone, T., Toh-e, A., and Yokosawa, H. Identification of ubiquitin-like protein-binding subunits of the 26 S proteasome. Biochem Biophys. Res Commun. 2002, 296, 813. 

Kameji, T., Hayashi, S., Igarashi, K., Tamura, T., Tanaka, K., and Ichihara, a. Ornithine decarboxylase is degraded by the 26 S proteasome without ubiquitination. Nature 1992, 360, 597-599. 

C., Sugasawa, K., Maekawa, T., Tanaka, K, Hoeijmakers, J. H., and Hanaoka, F., Interaction of hHR23 with S5a. The ubiquitin-like domain of hHR23 mediates interaction with S5a subunit of 26 S proteasome, J. 

Raasi, S. and Pickart, C. M., Rad23 ubiquitin-assodated domains (UBA) inhibit 26 S proteasome-catalyzed proteolysis by sequestering lysine 48-linked polyubiquitin chains, J. Biol. Biol, 2003, 278, 8951. 

Li, L, Deng, X. W. The COP9 signalosome an alternative lid for the 26 S proteasome Trends Cell Biol. 

Nguyen T, Sherratt PJ, Huang HC, Yang CS, Pickett CB. 2003. Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. Degradation of Nrf2 by the 26 S proteasome. J Biol Chem 278 4536 4541. 

Figure 19 The eukaryotic 26 S proteasome. Subunit compositions of the 19 S regulatory particle of Saccharomyces cerevisiae is shown on the left. The a and p rings of the 20 S proteasome, each of which consists of seven different subunits, are included to indicate how the base 19 S complex is linked to the core 20 S protease complex. The crystal structure of the 20s degradation chamber is shown in both side and top views (figure made using PDB 1RYP).

Hirano, Y., Murata, S., Tanaka, K., Shimizu, M., and Sato, R. Sterol regulatory elementbinding proteins are negatively regulated through SUMO-1 modification independent of the ubiquitin/26 S proteasome pathway. J Biol Chem 278 (2003) 16809-16819. 

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