Ruthenium oxo compounds

Carbon-carbon bonds can be selectively cleaved by ruthenium-oxo compounds, such as in the transformation of phenylcyclohexane to cyclohexanecarboxylic acid (equation 119).332... 

Ruthenium oxo compounds catalyze the oxidation of amides, e.g. -lactams, at the position a to the nitrogen, using peracetic acid as the oxidant, presumably via oxoruthenium intermediates [264]. 

Sequential O-deacetylation, 0-isopropylidenation, and acetylation transformed 80 into compound 81. O-Deacetylation of 81, and ruthenium te-traoxide oxidation of the product, gave the 2-oxo compound 82, which was converted into 83 by hydrogenation over a platinum catalyst and acetylation. ... 

Hydrogen peroxide converts morpholine into its 4-hydroxy derivative (50JA2280), but TV-alkyl morpholines yield 3-oxo compounds if ruthenium(VIII) oxide or sodium metaperiodate are used as oxidants (76S598). Chlorine at -70 °C oxidizes the thiomorpholine (116) to the dihydro-1,4-thiazine (117) (73JCS(Pl)l32l), but more vigorous conditions result in the formation of S-oxides. 

It was later found that this transformation can be also carried out using other transition metal-oxo compounds like ruthenium-oxo species [51] and osmium tetroxide [23, 24], which has been reviewed by Piccialli in 2007 [52]. 

Epimerization of 50 at C-3 furnished carba-a-DL-allopyranose (60). Stepwise, 0-isopropylidenation of 50 with 2,2-dimethoxypropane afforded compound 56. Ruthenium tetraoxide oxidation of 56 gave the 3-oxo derivative 57, and catalytic hydrogenation over Raney nickel converted 57 into the 3-epimer 58 exclusively. Hydrolysis of 58, and acetylation, provided the pentaacetate 59, which was converted into 60 on hydrolysis. ... 

Among the metal complexes used in electrocatalytic oxidation of organic compounds, polypyridyl oxo-ruthenium complexes have attracted special attention,494"508 especially [RuIV(terpy)(bpy)0]2+.495 197,499,500,502,504 This high oxidation state is reached from the corresponding Run-aqua complex by sequential oxidation and proton loss (Equations (75) and (76)). 

DR. THOMAS MEYER (University of North Carolina) Wagner de Giovanni, in my lab, is studying the reaction between an oxo ruthenium compound and N0 ... 

Hydroformylation - [CARBON MONOXIDE] (Vol 5) - [OXO PROCESS] (Vol 17) -of allyl alcohol [ALLYL ALCOHOL AND MONOALLYL DERIVATIVES] (Vol 2) -catalysts for [CATALYSIS] (Vol 5) -C-19 dicarboxylic acids from [DICARBOXYLIC ACIDS] (Vol 8) -of ethylene [ETHYLENE] (Vol 9) -of ethylene [PROPYL ALCOHOLS - N-PROPYLALCOLHOL] (Vol 20) -of maleate and fumarate esters [MALEIC ANHYDRIDE, MALEIC ACID AND FUMARIC ACID] (Vol 15) -phosphine catalyst [PHOSPHORUS COMPOUNDS] (Vol 18) -platinum-group metal catalysts for [PLATINUM-GROUP METALS] (Vol 19) -rhodium catalysis [PLATINUM-GROUP METALS, COMPOUNDS] (Vol 19) -ruthenium cmpds or catalyst [PLATINUM-GROUP METALS, COMPOUNDS] (Vol 19) -use of coordination compounds [COORDINATION COMPOUNDS] (Vol 7)... 

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