Resource assessment, criteria

These screening approaches require minimum information for the evaluation of pharmaceutically relevant properties. Compounds that do not meet a predetermined criterion are eliminated from further consideration. Guidance is obtained for further structure optimization via synthetic modification. Thus, pharmaceutical properties are assessed on the timescale of compound synthesis, resulting in an optimization while programs are still active. Therefore, unfavorable candidates are eliminated early and resources are focused on more promising drug candidates. 

These metals are considered hazardous under the Resource Recovery and Conservation Act of 1987 (RCRA) [4]. The RCRA metals occur in chemical forms that are soluble or insoluble in groundwater. The soluble species are of concern from the dispersibility viewpoint. Hence, the test criterion to evaluate whether a given waste stream needs stabilization prior to disposal is based on how much a given hazardous metal dissolves in water in a standardized test. This EPA test, called the Toxicity Characteristic Leaching Procedure (TCLP) [5], is used not only to identify which waste streams need treatment, but also to assess whether the treated waste form is suitable for disposal. This test also sets limits on how little of a hazardous metal is permitted to leach out from a given waste to pass the waste for disposal. If the test determines that the waste is not suitable for safe... 

Dispenses information Is primary learning resource Stresses inquiry Groups students according to ability (norm- referenced) Focuses on information Evaluates via classroom testing Facilitates learning experience Allows participants to serve as learning resources Stresses practical application Tries to help all participants perform to specified level (criterion-referenced) Focuses on performance Evaluates via on-the-job performance assessment... 

There is no single way of assessing and comparing the different proposals factors that must be taken into consideration include, for example, the extent to which the proposals are consistent with the company s long-term plans the risk attached to the proposals and the availability of the necessary resources even if the money is available. One important criterion, however, is the financial one which of the proposals will give the best retirm on the investment The usiral way of determining this is to use the method known as discounted cash flow. 

A methodology was described to assess the feasibihty of success in making commodity chemicals from renewable resources. The methodology uses a five-step process in the assessment. The first step is portfolio selection, and some of the key selection criteria are high theoretical yields from substrate, high market interest, and volume. The second phase involves initial economic screening and uses an economic criterion called the Fraction of Revenue for Feedstock (FRF). In this calculation, the cost of the feedstock is divided by the value of all the products, and the products that show the most promise are those where the fraction is smallest. This value takes into account the yields of the products derived from the various feedstock components. The third phase is a comparative analysis of bioprocessing routes that uses a raw material cost ratio, which... 

Biodegradability can bring benefits in specific applications, particularly at the end of life of some plastics products but it is not an end by itself and it should be highlighted that end-of-life is generally not the main source of environmental impact in a product life. Fitness for use is the main driver for plastic type selection for any application and, in the perspective of an optimised use of existing resources, eco-efficiency over the whole life cycle should be the main criterion against which the combined environmental and economic impacts of any product have to be assessed. 

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