Reflotron analyzer

Naka, S. (1987). Biochemical tests by dry chemistry. Med. Technol. IS, 950-954. Nanji, A.A., Sincennes, F., Poon, R. and Hinberg, I. (1987). Evaluation of the Boehringer Mannheim Reflotron analyzer. Clin. Chem. 33, 1254-1255. 

Kuba, K. and Luepker, R.V. (1988), Measurement of blood cholesterol with the Reflotron analyzer evaluated. Clin. Chem. 34, 426. 

E285 Rohac, M. and Gabl, F. (1986). Evaluation of two dry reagent systems Determination of glucose, cholesterol, and triacylglycerols with the Reflotron and Kodak Ektachem DT 60 analyzer. J. Clin. Chem. Clin. Biochem. 24, 790-791, Abstr. E 19,... 

E660 Miccoli, R., Bertolotto, A., Giovannitti, M.G., Tedesco, I., Leotta, L. and Na-valesi, R. (1990). Laboratory and field evaluation of Reflotron and DT-60 analyzers for cholesterol and triglyceride assay. Clin. Chem. 36, 1201-1202, Abstr. 1166. 

R58 Goitein, R.K., Sykes, R.L., Baer, D.M. and Belsey, R.E. (1987). An evaluation of a physician office laboratory chemistry analyzer, the Boehringer Mannheim Reflotron. Clin. Chem. 33, 938, Abstr. 282. 

Rohac, M., Hoemer, M. and GabI, F. (1987). Comparison of three desk top clinical chemistry analyzer Ektachem DT-60, Reflotron, and Vision. Ann. Clin. Biochem. 24, Suppl. 2, 94-95. 

Analyzer Ektachem 700 Ektachem DT-60 Reflotron Cobas Ready, Spotchem Seralyzer Stratus Opus... 

No final answer can be given to this question, for similar cases are also known in wet chemistry (for example, the Pack Analyzer ACA of DuPont de Nemours). Here, too, the apparatus or method is calibrated once for every batch and is rechecked daily or at regular intervals by means of the quality control sample. The system of dry chemistry can be viewed under the same aspect. The Ektachem system is known to be stable for more than 6 months, so that the apparatus or method need not be readjusted during this period but only supervised via quality control checks. The problem of calibration does not arise with Reflotron, since all the requisite data (calibration data) are stored on the reverse of the test slides. No data, however, are available on long-term studies of stability. The FDA has prescribed a 7-day or 30-day calibration rhythm for the Seralyzer system depending on the analyte to be analysed. 

When an assay system has been designed to analyze whole blood samples, specimen preparation time is essentially eliminated. Automated or semiautomated ion-selective electrodes, which measure ion activity in whole blood rather than ion concentration, have been incorporated into automated systems to provide certain test results within minutes of the drawing of a specimen. This approach is now commonly used for assaying electrolytes and some other common analytes. Another approach involves either manual or automated application of whole blood to dry reagent films and visual or instrumental observation of a quantitative change. This approach is exemplified by the Reflotron Plus. 

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