Receptors subfamilies

Glucocorticoid Receptor GR GCR GRL Nuclear Receptor Subfamily 3, Group C, Member 1 (NR3C1) Glucocorticoid Receptor Type II Mineralocorticoid Receptor MR MCR MRL Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2) Glucocorticoid Receptor Type I Aldosterone Receptor... 

Enterochromaffin cells are interspersed with mucosal cells mainly in the stomach and small intestine. In the blood, serotonin is present at high concentrations in platelets, which take up serotonin from the plasma by an active transport process. Serotonin is released on platelet activation. In the central nervous system, serotonin serves as a transmitter. The main serotonin-containing neurons are those clustered in form of the Raphe nuclei. Serotonin exerts its biological effects through the activation of specific receptors. Most of them are G-protein coupled receptors (GPCRs) and belong to the 5-HTr, 5-HT2-, 5-HT4-, 5-HTs-, 5-HT6-, 5-HT7-receptor subfamilies. The 5-HT3-receptor is a ligand-operated ion channel. 

In Arahidopsis, ethylene is perceived by a family of five receptors divided, on the basis of structural similarities, into ETRl-like subfamily 1 comprising ETRl and ERSf, and ETR2-like subfamily 2 consisting of ETR2, ERS2, and EIN4. ° Similar ethylene receptor subfamilies have been identified in several species. ... 

Noonberg SB, Benz CC. Tyrosine kinase inhibitors targeted to the epidermal growth factor receptor subfamily role as anticancer agents. Drugs 2000 59 753-767. 

Singh J, Dobrusin EM, Fry DW et al. Structure-based design of a potent, selective, and irreversible inhibitor of the catalytic domain of the erbB receptor subfamily of protein tyrosine kinases. J Med Chem 1997 40 1130-1135. 

Nishimura M, Naito S, Yokoi T. Tissue-specific mRNA expression profiles of human nuclear receptor subfamilies. Drug Metab Pharmacokinet 2004 19 135-149. 

Wurch T, Palmier C, Colpaert FC, Pauwels PJ. Sequence and functional analysis of cloned guinea pig and rat serotonin 5-HT1D receptors common pharmacological features within the 5-HT1D receptor subfamily. J Neurochem 1997 68 410-418. 

Lucaites VL, Nelson DL, Wainscott DB, Baez M. Receptor subtype and density determine the coupling repertoire of the 5-HT2 receptor subfamily. Life Sci 1996 59 1081-1095. 

Arch, R. H., and Thompson, C. B. (1998). 4-lBB and 0x40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor kappaB. Mol. Cell. Biol. 18, 558-565. 

The mannose receptor subfamily is a group of membrane-attached C-type lectins with multiple CRDs. Since most of these domains maintain neither calcium-binding nor sugarbinding properties, the term C-type lectin-like domain (CTLD) is more frequently used lately instead of the term CRD. The mannose receptor subfamily comprises four members including the mannose receptor, the M-type phospholipase A2... 

Ly49 killer cell lecdn-like receptor subfamily A, member 1. Analogous for human KIRs. A natural killer cell receptor. 

Reschly EJ, Krasowski MD. Evolution and function of the NR1I nuclear hormone receptor subfamily (VDR, PXR, and CAR) with respect to metabolism of xenobiotics and endogenous compounds. Curr DrugMetab. 2006 7 349-365. 

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