Reaction with acrylic acid

However, none of these compounds can be easily resolved except TM (16) Itself. Me prefer to resolve as early as possible, (page T 94), so It is better to carry out the Diels-Alder reaction with acrylic acid and resolve acid (19) before adding the phenyl group by a Grignard reaction. The benzylic alcohol group in (20) can be taken out by metal-anunonia reduction. Syrithesis ... 

Ring B of pyrimido[l,6-tf]pyrimidines has been most frequently synthesized from [3+3] atom fragments. The 6-aminopyrimidin-2-one derivative, cytidine 211, on reaction with acrylic acid under thermal conditions gave the pyrimido[l,6- ]pyrimidin-4,6-dione 212 <1996MI301> while reaction with 3-chloropropionaldehyde under base catalysis resulted in the pyrimido[l,6- ]pyrimidine-6-one 213 (Scheme 33) <1996MI501, 1996BAP209>. 

More recently, Gangneux et al (11) developed a method for grafting acrylic acid onto cellulose powder, "Solka Floe," for use in textile waste treatment. The cellulose was treated with ceric ion in aqueous solution prior to its reaction with acrylic acid. A benzene-acrylic acid solution was used for grafting to reduce homopolymerization. Presumably, the hydrated ceric ion would not diffuse into the monomer solution to initiate homopolymerization although the reverse could still take place. They obtained grafting yields up to approximately 70% accompanied by 45% homopolymer. In the present investigation, their method is extended to fibers and additional emphasis is placed on the reduction of homopolymerization. 

The reaction with acrylic acid deserves special attention, because acrylic acid is not usually a good Diels-Alder reagent. That the reaction proceeds catalytically and with high ee indicates the facile exchange of the (acyloxy)borane of the cycloadduct with the carboxylic group of unreacted acrylic acid, whereas the monoacrylated tartaric acid remains bound to boron (Fig. 1). 

Synthesis.—Type A Syntheses (S—C—N + C—C). The reaction between thioureas RNHCSNH2 and /3-aroylacrylic acids gives the A -thiazolin-5-ones (47), which may be converted into bicyclic compounds on treatment with hydrazine or hydroxylamine (see later).However, the reaction with acrylic acid amides simply leads to transamidation, giving ArCOCH=CHCONHCSNH2. ... 

Almost all the catalysts presented up to this point have also been tested in the Michael reaction with acrylic acid derivatives, typically acrylate esters and acrylonitrile. The usual situation found is that these kinds of acceptors furnish similar results to those observed in the same reaction with vinyl ketones, although in some cases a different behavior is observed. On the other hand, there are also some catalytic systems which have been exclusively tested on acrylate-type electrophiles, as will be shown in the following. 

The rate law is first order with respect to both [e ] and [R2S], where R = Me, Et, or Pr . The technique of continuously mixing solutions of solvated electrons (Na dissolved in NH3) with substrates in the cavity of an e.s.r. spectrometer continues to be used. Radical anions have been characterized in the reactions with acrylic acid and with some dicarboxylic acids. 

The reaction with acrylic acid deserves special attention, since it is usually not a good component in Diels-Alder reactions. The fact that the reaction proceeds cat-... 

Heck reaction with acrylic acid can be carried out at room temperature if diaryliodonium salts are taken as the arylating agents in water [95]. At room temperature, only one aryl group of the iodonium salt is transferred to the product ... 

Carbodi-imide-mediated reaction with acrylic acid-acrylamide copolymer... 

For these oligomers, it is preferred that n have a value of about 1 to 6. Modified block copolymers have been synthesized by coupling the above products with difunctional isocyanates (193) and with cycloaliphatic diepoxides (194). They were also used to synthesize radiation-curable diacrylates by means of a condensation reaction with acrylic acid (195). Other modifications of the oligomeric compounds include end capping with anhydrides to form acid-terminated oligomers (196) and reaction with polyols, anhydrides, and carboxylic acids to form low-viscosity, oil-free alkyds that are useful as coating intermediates (197). 

Grafting reactions on a polymer substrate, i.e. on the surface of a polymer film, can be carried out via radical generation processes. For example, hydrophobic hydrocarbon surfaces can be made more hydrophilic by a photografting reaction with acrylic acid. The photografting of a UV screen-type stabilizer would be highly desirable. 

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