Rauvolfia verticillata

Isolation of the stereospecific strictosidine s)mthase (STS) and formation of strictosidine with the 3a-(S) configuration proved conclusively that this was the natural precursor of the terpenoid indole alkaloids. Strictosidine occurs naturally in Rhazya stricta and the synthase has been isolated from a number of other species Amsonia salicifolia, A. tabemaemontam, Catharanthus pusillus, C. roseus, Rauvolfia verticillata, R. vomitoria, R. serpentina, Rhazya orientalis and Voacanga africana. The enzyme has been purified to homogeneity from R. serpentina (Hampp and Zenk, 1988). A comparison of the activity of STS from C. roseus roots, the only portion of the plant to contain ajmalicine, with that present in plant cell cultures producing the same alkaloid demonstrated that the plant cell cultures are far more metabolically active (Ziegler and Facchini, 2008). 

Spegatrine Aspidosperma spegazzinii Rauvolfia sprucei Rauvolfia verticiUata var. hainanensis Rauvolfia verticillata var. rubrocarpa... 

A bisquaternary alkaloid, dispegatrine (310), was isolated from the water-soluble fraction of the roots of Rauvolfia verticillata hainannensis 208). 

Hong B, Gao J, Wu J, Zhao C (2012) Chemical constituents from Rauvolfia verticillata and bioactivities research. Chem Nat Comp 48 276—280... 

The previous pioneering work by Court and coworkers resulted in the most comprehensive phytochemical analysis of Rauvolfia species. For instance, during their work on 10 mainland African species, 133 individual indole alkaloids were identified. Moreover, recently eight new indole alkaloids have been isolated from Rauvolfia species of mainland China and the structures of them were identified by Liu and colleagues. Seven novel indole alkaloids from the leaves and twigs of Rauvoffia verticillata were also identified. ... 

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