Quassia amara Quassin

Njar, V.C., T.O. Alao, J.I. Okogun, et aL 1995. AntifertUity activity of Quassia amara Quassin inhibits the steroidogenesis in rat Leydig cells in vitro. Planta Med. 61(2) 180-182. 

T riterp. azadirachtin-like tetranortritero. azadirachtin (neem teee,Azadirachta indicaA. Juss., Meliaceae, Ang. MI) Quassinoids (biosynthetically related to triterp.) including seco- and further degraded forms Quassia amara L., Sapindales, Ang. from Jamaica quassin DSII, and other metabolites Connolly 1997). 

Figure 5 Biological activities associated with quassinoids, from Simaroubaceae species, may not be linked to a common mechanism of action/ Different testing procedures have indicated insecticidal activity for quassin, anticancer activity for quassimarin (also present in Quassia amara) and antimalarial activity for simalikalactone-D/...

Quasslae lignum Quassia wood Quassia amara L. SURINAM Picrasma excelsa PLANCH. Simarubaceae MD Secotriterpenes (simariibalides) -0.25% quassin, neoquassin and 18-hydroxy-quassin (0.1%-0J.5%). Bl of the drug, 40000-50000 Bl of quassin/neoquassin, 17 x 10 Fig. 10... 

Neoquassin. Ih.Hydrt)xy-2.12-dimethoxypirrasa-2,12-d irne-i, /1 -dtone 3a,4t5,6a,7,7a,8tlla,Ilb,llc-deca-hydro-5-hydroxy-2,10-dimethoxy-3,8,l la,l lc-tetramethyl-phenanthro[10,l-bc]pyran-l,ll-dlone. C22HmO mol wt 390.46. C 67.67%, H 174%, O 24.59%. Found together with the quassin in the mixture of bitter constituents of the wood of Quassia amara L., Simaroubaceae. known in commerce as Surinam quassia. Forms quassin on oxidation. Isoln London eta/., J. Chem. Soc. 1950, 3431. Structure Valenta et al. Tetrahedron Letters 1960(20), 25 Carman, Ward, ibid. 1961, 317 Valenta et al. Tetrahedron 15, 100 (I960,... 

Picrasma exceisa (Sw ) Planch, or of Quassia amara L., Simaroubaceae. The first is known in commerce as Jamaica quassia, the second as Surinam quassia. Habit. Picrasma txelsa inhabits Jamaica and the Caribbeen Islands Quassia amara is a native of Brazil and Guiana and is cultivated in Colombia, Panama, and the West Indies. Quassin and neo quassin are the bitter principles of Surinam quassia picras-min, that of Jamaica quassia. These bitter pinctples are obtained in yields of 0.1-0.296 and appear commercially under the name of quassin. 

This reversal of orientation has been used to prepare (4) in a projected total synthesis of quassin (5), the bitter principle of Quassia amara, which contains... 

Synonyms Bitter ash Bitter wood Picrasma excelsa Quassia amara Definition Wood of Picrasma exceisa or Quassia amara, contg. bitter principle quassin Properties YIsh-wh. to bright yel. chips or fibrous coarse grains, si. odor, very bitter taste Uses Natural flavoring agent in foods and pharmaceuticals bitter tonic medicine (anthelmintic) extract as fly poison on flypaper surrogate for hops hair lotion alcohol denaturant... 

Scragg AH, Allan EJ (1994) Quassia amara (Surinam Quassia) in vitro culture and the production of quassin. In Bajaj YPS (eds) Biotechnology in agriculture and forestry, vol 26. Medicinal and aromatic plants VI. Springer, Heidelberg, pp 316-326... 

The well-known bitter principle of the wood of Quassia amara L., quassin, has two enone chromophores within its structure shown in Figure 10. Accordingly, its CD exhibits a typical couplet at 266 nm (Ae =-t-10.4) / 242 nm (Ae = -9.5) arising... 

Quassia amara, whole plant, quas quassin, neoquassin aphid and other sucking insect control, also medidnal 25... 

Quadrangularin A, 2153, 2162 Quadmpole-linear ion trap (Q-LIT), 1125 Quadmpole time of flight (Q-TOF), 1125 Quantitative electronic structure activity relationship (QESAR), 3352 Quantitative H NMR, 1037 Quantitative structure activity relationship (QSAR), 3351 Quantum dots, 1036 Quassia, 3780 Q. amara, 3781 Q. indica, 3718 Quassin, 3347, 3778... 

Surinam quassia (Q. amara) contains quassin, quassinol, 18-hydroxyquassin, and neoquas-sin, while Jamaican quassia (P. excelsa) contains isoquassin (picrasmin), neoquasin, and 18-hydroxyquassin as their bitter principles (list and horhammer). These bitter principles are reported to be about 50 times more bitter than quinine (stahl). 

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