Pyrantel tartrate

Equine anthelmintic, for the prevention of strongylus vulgaris larval infestation in horses Strongid C Pyrantel tartrate Dehydrated Alfalfa meal, wheat middlings, cane molasses, mineral oil... 

Pyrantel exliibits absorption, distribution, biotransformation, and elimination profiles similar to those of morantel. Pyrantel tartrate is well absorbed with peak plasma levels occurring 2-3 h after dosing. In ruminants, urinary excretion accounts for about 25% of the administered dose, while much of the remainder passes unchanged in feces. However, the pamoate salt is very poorly absorbed, most of the dose being excreted in feces. 

Infra-red Spectrum. Principal peaks at wavenumbers 1640,1605, 1305, 1208, 1132, 1065 (pyrantel tartrate, KBr disk). 

Pyrantel embonate, 947 Pyrantel pamoate, 947 Pyrantel tartrate, 947 Pyrazinamide, 947 Pyrazinecarboxamide, 947 Pyrazinecarboxylic acid, 947 Pyrazinoic acid amide, 947 Pyrazolopyrimidinol, 327 Pyrazolylethylamine, 335 Pyrethrin I, 77, 85 Pyrethrin II, 77, 85 Pyrethrolone, 77 Pyribenzamine, 1052 Pyridacil, 873... 

SYNS BANMINTH CP 10423-18 PYRANTEL TARTRATE PYREQUAN TARTRATE (E)-l,4,5,6-... 

Standard dose rate in USA is 6mg/lq pyrantel pamoate standard dose in Europe is 19mg/kg pyrantel embonate pyrantel tartrate dose is 2.6mg/kg daiy in feed tapeworm dose is twice standard dose >50% iicacy... 

Cornwell R L, Jones R M 1968 Field trials in horses with pyrantel tartrate. Veterinary Record 82 586-587 Costa A J, Barbosa O F, Moraes F R et al 1998... 

Pyrantel tartrate has a somewhat higher safety factor than tetramisole, according to published accounts (see Table I), though neither approaches the high therapeutic index reported for thiabendazole. 

Pyrantel tartrate was described as a colorless crystalline material which is soluble in water (180 mg/ml). Solutions are sensitive to ultraviolet light, undergoing trans-cis isomerization upon prolonged exposure. Storage in dark bottles is sufficient to protect solutions against light-in-... 

New anthelmintic agents which are already in use in veterinary medicine have been found in two cyclic amidine derivatives, pyrantel tartrate (Banminth, Strongid) (269) and morantel tartrate (Banminth II) (270). For references concerning their evaluation in sheep, cattle, pigs, horses, dogs, and man see Ref. 260. These compounds are most probably prepared by condensation of the appropriate thiophen aldehyde with 1,4,5,6-tetra-hydro-l,2-dimethylpyrimidine. Extensive investigations on structure-... 

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