Pyrantel embonate

Pyrantel embonate, 947 Pyrantel pamoate, 947 Pyrantel tartrate, 947 Pyrazinamide, 947 Pyrazinecarboxamide, 947 Pyrazinecarboxylic acid, 947 Pyrazinoic acid amide, 947 Pyrazolopyrimidinol, 327 Pyrazolylethylamine, 335 Pyrethrin I, 77, 85 Pyrethrin II, 77, 85 Pyrethrolone, 77 Pyribenzamine, 1052 Pyridacil, 873... 

Standard dose rate in USA is 6mg/lq pyrantel pamoate standard dose in Europe is 19mg/kg pyrantel embonate pyrantel tartrate dose is 2.6mg/kg daiy in feed tapeworm dose is twice standard dose >50% iicacy... 

Only pyrantel salts have label claim for good efficacy (> 90%) for the removal of tapeworm infections. Use pyrantel pamoate 13.2 mg/kg p.o. (USA), or pyrantel embonate 38 mg/kg p.o. (Europe), or praziquantel 1 mg/kg p.o. 

Sangster N C 1999 Pharmacology of anthelmintic resistance in cyathostomes will it occur with the avermectin millbemycins. Veterinary Parasitology 85 189-204 Tarigo-Martinie J L, Wyatt A R, Kaplan R M 2001 Prevalence and clinical implications of anthelmintic resistance In cyathostomes in horses. Journal of the American Veterinary Medical Association 218 1957-1960 Taylor S M, Kenny J 1995 Comparison of moxidectin with ivermectin and pyrantel embonate for reduction of faecal egg count in horses. Veterinary Record 137 516-518 Uhlinger C 1990 Effects of three anthelmintic schedules on the incidence of coiic in horses. Equine Veterinary Journal 22 251-254... 

Pamoate, CmHnNjO,S, C P-10423-16, pyrantel embonate, Antiminth, Cabaniril, Combantrin, Early Bird, Helmex, Piranver. Tasteless, yellow crystalline powder. Insol in water. Mixture with oxantel pamoate (1 1), QuantreL therap cat Anthelmintic (Nematodes). therap cat (Vet) Anthelmintic. 

Committee for Veterinary Medicinal Products, Pyrantel Embonate, EMEA/MRL/491/98-FINAL available from http //www.ema.europa.eu. 

Pyrantel is usually given as the embonate or pamoate in a single dose of 10 mg/kg, and adverse reactions rarely... 

Three pyrantel salts (pamoate, embonate and tartrate) are indicated for use in the horse. The pyrimidines are selective agonists at synaptic and extrasynaptic nicotinic acetylcholine receptors on nematode muscle cells, which produce spastic paralysis of the parasites. 

In veterinary medicine, the main tetrahydropyrimidine drugs are pyrantel and morantel. Pyrantel is used widely in horses as the pamoate (embonate a naphthoic acid derivative) salt and it is active against a range of roundworms. As the tartrate and citrate, it is used in cattle, sheep and pigs in some countries. However, in the European Union (EU), the maximum residue limit (MRL) only covers the use in horses. Morantel, usually as the citrate or tartrate is used to treat parasitic infestations in a number of species. Pyrantel, in combination with ivermectin is used to treat susceptible parasites in dogs and in combination with praziquantel (see section 12.2.7), parasites in cats and dogs. Oxantel, in combination with pyrantel and praziquantel is used to treat parasitic disease in... 

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