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Psychopharmacology drug action

Healy, D. (2002). The Creation of Psychopharmacology. Cambridge, MA Harvard University Press. Hyman, S.E. Nestler, E. J. (1996). Initiation and adaptation a paradigm for understanding psychotropic drug action. Am.. Psychiatry, 153(2), 151-62. [Pg.166]

Feldon J, Weiner I (1991) Effects of haloperidol on the multitrial partial reinforcement extinction effect (PREE) evidence for neuroleptic drug action on nonreinforcement but not on reinforcement. Psychopharmacology (Berl) 705 407 114. [Pg.380]

Research into the properties of opiates has provided more insights into the processes that make up psychopharmacological actions than any other class of drug this is because opiates bind to receptor sites that are affected by endorphins - the brain s indigenous opiates. These endorphins are implicated in pain thresholds, natural highs and our capacity for addiction to opiates. [Pg.104]

Costall B, Jones BJ, Kelly ME, Naylor RJ, Onaivi ES, Tyers MB (1990b) Sites of action of ondansetron to inhibit withdrawal from drugs of abuse. Pharmacol Biochem Behav 36 97-104 Cryan JF, Bruijnzeel AW, Skjei KL, Markou A (2003) Bupropion enhances brain reward function and reverses the affective and somatic aspects of nicotine withdrawal in the rat. Psychopharmacology 168 347-358... [Pg.429]

Other plants known to contain psychoactive compounds include hellebore, which was used for centuries in Europe to treat mania, violent temper, mental retardation and epilepsy. However, a drug of major importance in modern psychopharmacology arose from the discovery by medicinal chemists of the alkaloids of Rauwolfia serpentina, a root which had been used in the Indian subcontinent for centuries, not only for the treatment of snake bite but also for alleviating "insanity". Understandably, the mechanism of action of reserpine, the alkaloid purified from Rauwolfia serpentina, helped to lay the basis to psychopharmacology by demonstrating how the depletion of central and peripheral stores of biogenic amines was correlated with a reduction in blood pressure and tranquillization. [Pg.228]

Carnwath T, Gabbay M Barnard f (2000). A share of the action general practitioner involvement in drug misuse treatment in Greater Manchester. Drugs Education, Prevention and Policy, 7, 235-44 Carnwath T, Garvey T Holland M (2002). The prescription of dexamphetamine to patients with schizophrenia and amphetamine dependence. Journal of Psychopharmacology, 16, 372-7... [Pg.152]

For scientific reasons, it is always desirable to focus on one and only one thing in any given experiment. In psychopharmacology, this desideratum is expressed in so-called clean drugs that have one and only one action. [Pg.211]

Taking direction from psychopharmacological studies indicating that drugs with known mechanisms of action on receptors or enzymes predictably alter symptoms in a specific psychiatric disorder... [Pg.102]


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See also in sourсe #XX -- [ Pg.62 , Pg.63 ]




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