Proteins antigenic foreign

As mentioned on p. 1854, an important function of proteasomes is formation of short antigenic peptides for use by the immune system.664 Inhibition of proteasome activity reduces or prevents antigen presentation (Chapter 31).665 666 In this immune surveillance system mature proteins of host cells are cut up and checked for self-identity. The checking also includes the rapidly degraded imperfect proteins and foreign proteins from invading organisms or viruses.667 6673... 

Antibodies Specific proteins produced by the body s immune system that bind with foreign proteins (antigens)... 

Figure 33.32. Presentation of Peptides from Internalized Proteins. Antigen-presenting cells bind and internalize foreign proteins and display peptides that are formed from the digestion of these proteins in Class II MHC proteins.

Is antigenic (foreign protein derived from beta-hemolytic streptococci). This causes a problem if recent past use or infection—strep antibodies may 4- activity... 

An autoimmune disorder is a malfunction of the body s immune system, causing the body to attack its own tissues [69]. Normally, the immune system can distinguish what is self from what is not self through the recognition of specific proteins called antigens. Foreign... 

Antigens, foreign macromolecules, predominantly proteins, carbohydrates and nucleic acids, that trigger the immune response, usually performed by production of defense proteins, known as antibodies [J. Kuby, Immunology (2nd edn.). Freeman, 1994]. 

An antibody is a protein (one of the immunoglobulins) used by the immune system of a mammal to identify and neutralize antigens (foreign objects like bacteria, viruses and others). Each antibody recognizes a specific... 

Antibody A protein that binds to a specific target molecule called an antigen. Foreign cells that infect your body are marked by antibodies and destroyed by lysis (bursting them open with fluid) or gobbled up by macrophage cells. 

In the rat, AgB-associated differences in response to a number of synthetic polypeptide and foreign protein antigens have been described . In the chicken, the B-locus, or a linked genetic factor, has been found to control resistance to Marek s disease (an avian leukosis virus-induced lymphoma), and also to autoimmune thyroiditis . Differences in response to the synthetic polypeptide (T,G)-A-L have also been observed . An extremely interesting observation in the chicken indicates a requirement for shared products of the same MHC haplotype in order for effective T cell—B cell cooperation to take place, as in the mouse. 

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