Proteins immunoglobulin

Antibody A protein (immunoglobulin) produced by humans and higher animals in response to exposure to a specific antigen, and characterized by specific reactivity with its complementary antigen. 

Protective and exploitive proteins Immunoglobulins Thrombin Eibrinogen Antifreeze proteins Snake and bee venom proteins Diphtheria toxin Rtcin... 

The chapter on plasma proteins, immunoglobulins, and blood coagulation in the previous edition has been split into two new chapters on plasma proteins and immunoglobuhns and on hemostasis and thrombosis. 

Casein can be precipitated from solution by any of several salts. Addition of (NH4)2S04 to milk to a concentration of 260 g 1 1 causes complete precipitation of the casein together with some whey proteins (immunoglobulins, Ig). MgS04 may also be used. Saturation of milk with NaCl at 37°C precipitates the casein and Igs while the major whey proteins remain soluble, provided they are undenatured. This characteristic is the basis of a commercial test used for the heat classification of milk powders which contain variable levels of denatured whey proteins. 

Figure 26-16 shows the isolation of the protein immunoglobulin G (IgG) by affinity chromatography on a column containing covalently bound protein A. Protein A binds to... 

Molecular components Antibacterial peptides (defensins, complement, acute-phase proteins) Immunoglobulins... 

When poly(ethylene oxide) (PEO) silane was grafted onto oxidized PDMS stamps it acts as a protein repellent layer. This property was utilized to design a flat stamp with regions that can attract proteins (nonmodified PDMS) and regions modified with PEO that have protein-repellent properties. The local modification of native PDMS was conducted by oxidation in 02-plasma with the application of a metal mask (areas that were covered by the mask were not oxidized and not modified). Proteins (immunoglobulin G, IgG) were transferred successfully to the glass substrates... 

Up to the present time, various techniques of nonisotopic immunoassay have been developed. Substances to be measured by these techniques include hormones (peptide and nonpeptide), biologically active trace substances, carrier proteins, immunoglobulins, viruses, tumor markers, antibodies against microorganisms (viruses, bacteria, and parasites), autoantibodies, etc. Innumerable papers concerning nonisotopic immunoassay have been published, and enzyme (15, Kl, N5, N6, PI, S2, V4, W9) and fluores-... 

Antibody activity is associated with three major classes of plasma proteins, immunoglobulins that are synthesized in the plasma cells and lymphoid cells,... 

Antibodies (ab) are high-molecular weight soluble proteins (immunoglobulins) produced by organisms in response to foreign substances (antigens, ag), with whom they form immunochemical complexes ... 

Passive targeting makes use of alteration of the pharmacokinetics of vectors by shielding them from binding to blood cells, plasma proteins, immunoglobulins, unwanted tissues, or to each other, allowing them to circulate for longer periods of time in the blood and accumulate in specific tissues with leaky blood vessels (such as tumors). 

Antibodies, proteins immunoglobulins) produced by B lymphocytes or B cells responsible for humoral immunity. An enormously diverse collection of related proteins mediates humoral immunity that is most effective against bacterial infections and the extracellular phases of viral infec-... 

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