Propoxyphene napsylate

I Brand Name(s) (propoxyphene napsylate) Darvon-N Combinations... [Pg.1044]

Mild to moderate pain PO (propoxyphene hydrochloride) 65 mg q4h as needed. Maximum 390mg/day. PO (propoxyphene napsylate) 100 mg q4h as needed. Maximum 600 mg/day. [Pg.1044]

Diphenylpropylamine derivatives propoxyphene hydrochloride propoxyphene napsylate... [Pg.626]

A 76-year-old woman taking lisinopril 20 mg/day and metoprolol for hypertension developed headaches, nausea, and a tingling sensation in her arms. Her serum sodium was 109 mmol/1, with a serum osmolality of 225 mosm/kg, urine osmolality of 414 mosm/kg, and urine sodium of 122 mmol/1. She had taken diclofenac 75 mg/day for arthritic pain for 6 years and naproxen for about 1 month. Propoxyphene napsylate and paracetamol had then been substituted and zolpidem had been started. A diagnosis of SIADH was postulated and thyroid and adrenal causes were excluded. Lisinopril was withdrawn and fluid was restricted to 100 ml/day. The serum sodium gradually corrected to 143 mmol/1. [Pg.615]

I. M. Jalal and S. I. Sa sa, Simultaneous determination of dextro-propoxyphene napsylate, caffeine, aspirin and salicylic acid in pharmaceutical preparations by reversed-phase HPLC, Talanta, 37 1015 (1984). [Pg.434]

Propoxyphene Napsylate oral suspension Propoxyphene Napsylate tablets Glass or Stainless Steel, 0.6 M x 3 mm I.D. 3% G2/S1AB Helium 160 FID n-Tricosane USP (24, p. 1425)... [Pg.480]

Gruber, C.M., Jr. Stephens, V.C. Tirrell, P.M. Propoxyphene napsylate chemistry and experimental design. Toxicol. Appl. Pharmacol. 1971, July, 19 (3), 423 26. Campbell, J.A. Slater, J.G. Modification of physical properties of certain antitussive and antihistaminic agents by formation of A-cyclohexylsulfamate salts. J. Pharm. Sci. 1962, Oct, 51, 931-934. [Pg.3187]

A. Avoid propoxyphene napsylate for pain relief as it can interact with her valproic acid therapy. [Pg.44]

Propoxyphene Napsylate, USP. Propoxyphene nap-sylale. (+ )-a-4-dimethylamino-3-melhyl-1.2-diphenyl-2-bulanol propanoate (c.sicr) 2-naphlhylenc.sulfonalc (salt) (Darvon-N). is very slightly soluble in water, but soluble in alcohol, chloroform, and acetone. The napsylate salt of propoxyphene was introduced shortly before the patent on Darvon expired. The insoluble salt form is claimed to be less prone to abu.se because il cannot be readily dissolved for injection and. on oral administration, gives a slower, less pronounced peak bhxxl level. [Pg.749]

Synonyms Darvocet-N Darvon Darvon-N Darvon pulvules Propoxyphene hydrochloride Propoxyphene napsylate Wygesic Chemical/Pharmaceutical/Other Class Synthetic opioid... [Pg.2127]

PROPOXYPHENE/ACETAMINOPHEN (Propoxyphene hydrochloride/Acetaminophen, Propoxyphene hydrochloride/acetaminophen tablets 65 mg propoxyphene hydrochloride/650 mg acetaminophen, propoxyphene napsylate/ acetaminophen Darvocet-N 50 tablets 50 mg propoxyphene napsylate/325 mg acetaminophen, Darvocet A500 tablets 100 mg propoxyphene napsylate/500 mg acetaminophen, Darvocet-N 100 tablets 100 mg propoxyphene)... [Pg.595]

CAS Registry No. 469-62-5 (propoxyphene), 1639-60-7 (propoxyphene hydrochloride), 26570-10-5 (propoxyphene napsylate monohydrate), 55557-30-7 (l-form propoxyphene napsylate monohydrate), 2338-37-6 (1 form propoxyphene), 17140-78-2 (l-form propoxyphene napsylate anhydrous)... [Pg.1189]

Gruber, J.C.M., Stephens, V.C. and Terrill, P.M. (1971) Propoxyphene napsylate chemistry and experimental design. Toxicol. Appl. Pharmacol. 19 423-426. [Pg.685]

Quantitation of Propoxyphene and Its Major Metabolite in Heroin Addict Plasma After Large Dose Administration of Propoxyphene Napsylate J. Pharm. Sci. 64(3) 429-433 (1975) CA 83 22163w... [Pg.187]

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