Product quality/consistency

BE- Intelligent equipment process monitoring for consistent finished product quality fIMPROQ) D. Farrington Bribsh Steel PLC... 

Crystallization process control is desirable from a number of standpoints. The primary objective is often to meet customer requirements by achieving consistent product quality to a desired specification of crystal size, size distribution and purity. Secondly, process requirements often dictate maintenance of stable crystallizer operation, the avoidance of fines and encrustation, and the minimization of subsequent downstream processing. 

PEs, as other polymers, exhibit nonlinear behavior in their viscous and elastic properties under practical processing conditions, i.e., at high-shear stresses. The MFI value is, therefore, of little importance in polymer processing as it is determined at a fixed low-shear rate and does not provide information on melt elasticity [38,39]. In order to understand the processing behavior of polymers, studies on melt viscosity are done in the high-shear rate range viz. 100-1000 s . Additionally, it is important to measure the elastic property of a polymer under similar conditions to achieve consistent product quality in terms of residual stress and/or dimensional accuracy of the processed product. 

The successful and profitable conduct of a frozen food quality program requires suitable and workable standards of product quality and condition, and suitable methods for determining the degree of product conformance with the standards. The methods used may be either subjective or objective in character, or a combination of both the most consistent and reproducible results will be obtained with objective methods. Present-day frozen food standards are, for the most part, based upon subjective methods of quality determination. These are certainly better than none at all but they are subject to considerable misinterpretation and human error, and for this reason leave much to be desired in providing a sound basis for quality control. 

Complex nutrients, such as yeast extract, are variable in composition and consequently it is difficult to maintain process reproducibility within the narrow window required to produce a product of consistent quality. 

It should be recognized that surface finish can be more than just a cosmetic standard. It also affects product quality, mold or die cost, and delivery time of tools and/or products. The surface can be used not only to enhance clarity for the sake of appearance but to hide surface defects such as sink and parting marks. The Society of Plastics Engi-neers/Society of Plastics Industries standards range from a No. 1 mirror finish to a No. 6 grit blast finish. A mold finish comparison kit consisting of six hardened tool steel pieces and... 

Based on over a century of worldwide production of billions of plastic products, they can be designed and processed successfully, meeting high quality, consistency, long life, and profitability. All that is needed is understanding the behavior of plastics and properly applying these behaviors. 

The evaporation pathway performed by the Dryex system allows for the reduction of 1,4-dioxane without any deterioration of the other chemical characteristics of the FAES product, resulting in a consistent improvement of the product quality. 

The final element which regulations address is quality. Safety and fitness for purpose, as discussed above, are two of the characteristics that you would associate with a quality product. However, these characteristics alone would not describe a quality product. For any product or service to be considered quality you would also expect it to be reliable and consistent. Additionally in the context of medical products, quality means a requirement to demonstrate conformance to agreed specifications or applicable standards for content, purity and stability. Many organisations, from manufacturers to service providers, voluntarily apply quality assurance systems in order to more effectively meet their customers needs on a consistent basis. However,... 

All stages of antibiotic manufacture from fermentation through to finished product are governed by the code of good manufacturing practice (GMP), of whieh quality eontrol is one aspect. GMP requires that there should be a eomprehensive system, so designed, documented, implemented and controlled, and so furnished with personnel, equipment and other resourees as to provide assuranee that products will consistently be of a quality appropriate to their intended use. ... 

Good manufacturing practice (GMP) comprises that part of quality assurance which is aimed at ensuring that a product is consistently manufactured to a quality appropriate to its intended use. GMP requires that (i) the manufacturing process is fully defined before it is commenced and (ii) the necessary facilities are provided. In practice, this means that personnel must be adequately trained, suitable premises and equipment employed, correct materials used, approved procedures adopted, suitable storage and transport facilities available and appropriate records made. 

The purpose of this section of an application is to establish that the proposed manufacturing process is suitable and that it will yield consistently product of the desired quality. The concept is closely related to GMP and the detail of conventional manufacturing process validation may not be required. However, data will normally be required for nonstandard manufacturing processes (particularly nonstandard sterilization processes) and for those aspects of manufacture that are critical in terms of product quality, e.g., in the manufacture of modified-release products the quality, safety, or efficacy of which will be affected by the method of manufacture. 

Batch production Sprouting is carried out in batches, so the product quality is more consistent than that obtained during the continuous processing of biomass as is necessary with whole plant material. One batch in the bioreactor is a production lot of the protein. 

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