ProDom

PRODOM provides a clustering based on SWISS-PROT and SP-TrEMBL (Bairoch and Apweiler, 1999). PRODOM also contains a clustering for complete genomes in PRODOM-CG, where each genome has been separately processed with MKDOM2. 

Each SWISS-PROT entry consists of general information about the entry (e.g., entry name and date, accession number), Name and origin of the protein (e.g., protein name, EC number and biological origin), References, Comments (e.g., catalytic activity, cofactor, subuit structure, subcellular location and family class, etc.), Cross-reference (EMBL, PIR, PDB, Pfam, ProSite, ProDom, ProtoMap, etc.), Keywords, Features (e.g., active site, binding site, modification, secondary structures, etc.), and Sequence information (amino acid sequence in Swiss-Prot format, Chapter 4). 

Corpet, F Gouzy, J. Kahn, D. (1999). Recent improvements of the ProDom database of protein domain families. Nucleic Acids Res 27, 263-7. 

PRODOM Database of protein domains based on BLAST sequence alignment http //www.toulouse.inra.fr/prodom.html INRA, FR, F. Corpet et al. [75]... 

Interpro Combination of the major protein family databases (PRINTS, PROSITE, Pfam, ProDom) Cl dl. http // www.ebi.ac.uk/ interpro/ EBI, Cambridge, R. Apweiler et al. [76, 300]... 

Corpet, F., et al., ProDom and ProDom-CG tools for protein domain analysis and whole genome comparisons. Nucleic Acids Res, 2000. 28(1) p. 267-9. 

DOMO [21] contain protein families and their alignments, so that changes in the proteins can be observed. Sequences also share domains, or modules, and the ProDom [20] and Smart [2] databases contain these domains and the proteins which fit those domains. 

DR PRODOM [Domain structure / List of seq. sharing at least 1 domain]... 

ProDom [20,21] is a collection of protein domain families automatically derived from the Swiss-Prot and TrEMBL databases using a novel approach based on recursive PSI-BLAST searches. 

Servant, F., C. Bru, S. Carrere, E. Courcelle, J. Gouzy, D. Peyruc, and D. Kahn. 2002. ProDom Automated clustering of homologous domains. Brief Bioinform 3 246-51. 

ProDom (http //protein.toulouse.ima.fr/prodom.html)... 

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