Problem reporting

The EDA and USP have developed the Dmg Product Problem Reporting Program to detect performance problems of marketed dmg products. 

To provide staff with the necessary organizational freedom you will need one or more problem-reporting procedures and some policies that give staff the freedom to identify, record, and report problems relating to the product, process, and quality system. 

You can do this by providing the evidence of previous audit results and problems reported by other means. 

Do establish a means of promptly responding to subcontractor queries and problem reports. 

This is the version of Gaussian 94 that is running, in this case. Revision C.3. Include this information in any questions or problem reports you send to Gaussian, Inc. 

Ozonoff D, Cohen ME, Cupples A, et al. 1987. Health problems reported by residents of a neighborhood contaminated by a hazardous waste facility. Am J Ind Med 11 581-597. 

In an acetone extract from a neoprene/SBR hose compound, Lattimer et al. [92] distinguished dioctylph-thalate (m/z 390), di(r-octyl)diphenylamine (m/z 393), 1,3,5-tris(3,5-di-f-butyl-4-hydroxybenzyl)-isocyanurate m/z 783), hydrocarbon oil and a paraffin wax (numerous molecular ions in the m/z range of 200-500) by means of FD-MS. Since cross-linked rubbers are insoluble, more complex extraction procedures must be carried out (Chapter 2). The method of Dinsmore and Smith [257], or a modification thereof, is normally used. Mass spectrometry (and other analytical techniques) is then used to characterise the various rubber fractions. The mass-spectral identification of numerous antioxidants (hindered phenols and aromatic amines, e.g. phenyl-/ -naphthyl-amine, 6-dodecyl-2,2,4-trimethyl-l,2-dihydroquinoline, butylated bisphenol-A, HPPD, poly-TMDQ, di-(t-octyl)diphenylamine) in rubber extracts by means of direct probe EI-MS with programmed heating, has been reported [252]. The main problem reported consisted of the numerous ions arising from hydrocarbon oil in the recipe. In older work, mass spectrometry has been used to qualitatively identify volatile AOs in sheet samples of SBR and rubber-type vulcanisates after extraction of the polymer with acetone [51,246]. 

Radiochemical Problems. Report A/Conf. 8/P/725. Proceedings, 1st Internal Conference on the Peaceful Uses of Atomic Energy, Geneva 1955, Vol. 7, S. 44. 

Conclusions. Based on the results of SEM, FTIR spectroscopy, and TGA analyses performed on the "good" and "bad" samples of white packaging film, the brittleness problem reported for the packages appears to have been caused primarily by degradation of the central opaque polyethylene layer. 

Parrott AC, Buchanan T, Scholey AB, Heffernan T, Ling J and Rodgers J (2002). Ecstasy/ MDMA attributed problems reported by novice, moderate, and heavy users. Human Psychopharmacology, 17, 309-312. 

The problem of the nucleophilicity of amides in glycosylation reactions is not limited to the sulfoxide method and has been shown to result in the formation of glycosyl imidates from intermolecular reaction with activated donors. It appears that this problem may be suppressed by the prior silylation of the amide [348,349]. Accordingly, it may be sufficient to operate the sulfoxide method with an excess of triflic anhydride when amides are present so as to convert all amides into O-triflyl imidates, which are then hydrolyzed on work-up. Despite these problems, several examples have been published of successful sulfoxide glycosylation reactions with acceptors carrying remote peptide bonds [344,345] and with donors coupled to resins via amide-based linkages [346,347], with no apparent problems reported. Sulfonamides and tertiary amides appear to be well tolerated by the sulfoxide method [340,350],... 

While the various strategies described above have proven promising, SOFC electrodes remain largely empirically understood and far from optimized and suffer from numerous short- and long-term degradation problems. Reported performances vary tremendously with many unknown variables at work and limited understanding as to how materials properties and microstructure relate to performance and long-term stability. ... 

A wide range of sleep disturbances has been documented in PD (Larsen, 2001). In a population-based survey of sleep disorders in PD, Tandberg et ah (1998) reported nocturnal sleeping problems in 60% of PD patients compared to 33% in healthy controls and 46% in elderly with diabetes mellitus. The most common problem reported was sleep fragmentation, which was found in 39% of PD and only 12% of normal elderly controls, whereas inability to fall asleep did not differ between the groups. 

Why is this At least part of the reason seems to reside in the well-rehearsed belief that the family caused the problem in the first place through dysfunction and abuse. Many people with drug problems report terrible childhoods marked by parental alcohol or drug use, by neglect or physical or sexual abuse. If this is the case, what could be the possible rationale for any further involvement of the extended family ... 

Crunen, A.A., Achenbach, T.M., and Verhulst, F. (1997) Comparisons of problems reported by parents of children in 12 cultures total problems, externalizing, and internalizing. J Am Acad Child Adolesc Psychiatry 36 1269—1277. 

Electric Power Research Institute (1985). Application of Biotechnology to PCB Disposal Problems. Report No. EPRI CS-3807, Project No. 1263-16, Palo Alto, CA. 

Comprehensive records of complaints received either directly from the customer or through a drug problem reporting program should be reviewed. Furthermore, a record of any follow-up investigation of such complaints is mandatory [6] and should be part of this fde. Review of customer complaint records can furnish a useful overview of process performance and possibly hint at product problems. Complaint analysis should therefore be viewed as a meaningful adjunct to the critical process step and control test selection process. 

Qualification and validation reports Ongoing evaluation Problem reporting/resolution Operational plans Validation fde Internal audits... 

Software release Master copy and backup Version control Software replication Problem reporting/resolution Fault notification to customers... 

Key Problem reporting and Operational audit Periodic review... 

Cannibalism is another problem reported in organic laying hens. It is known that several factors are involved in triggering cannibalism in a flock. These include breed, feed composition, rearing environment, external parasites and other management factors (Berg, 2001). 

Dumbauld, R. K. H. E. Cramer J. W. Barry "Application of meteorological prediction models for forest spray problems." Report No. TECOM 5-C0-403-000-051, U. S. Army Dugway Proving Ground, UT, 1975. 

Environmental Mercury Mercury/methylmercury Reverse phase Problems reported Harrington and Catterick (1997)... 

Specific Piping System Problems Reported as Major Incidents... 

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