8-Prenylated flavonoids

El-Bassouny A, Abouzid S. (2010) Anew prenylated flavonoid with antibacterial activity from propolis collected in Egypt. Nat Prod Commun 5 43 5. 

Recent developments in delayed extraction TOF allow higher resolving power and mass accuracy, and this method in the reflector mode has been used for accurate measurement of the mass of several compounds including two prenylated flavonoids. However, the performance of the MALDI-TOF instrument was not better than those of the FAB and FT-ICR MS instruments, and insufficient to give acceptable accuracy for literature reporting. 

Abegaz, B.M. et al., Prenylated flavonoids, monoterpenoid furanocoumarins and other constituents from the twigs of Dorstenia elliptica (Moraceae), Phytochemistry, 65, 221, 2004. 

Magalhaes, A.F. et al., Prenylated flavonoids from Deguelia hatschbachii and their systematic significance in Deguelia, Phytochemistry, 57, 77, 2001. 

Quercetin and a selection of naturally occurring prenylated flavonoids used as antiinflammatory agents in Chinese medicine were also tested for their ability to inhibit the... 

Chi, Y.S. et al., Effects of naturally occurring prenylated flavonoids on enzymes metabolizing arachidonic acid cyclooxygenases and lipoxygenases, Biochem. Pharmacol., 62, 1185, 2001. 

Aspects on substitution patterns of prenylated flavonoids and their derivatives including the frequency of occurrence have been discussed in detail. Thus, these aspects will not be... 

Mitscher, L.A. et al. Antimicrobial agents from higher plants prenylated flavonoids and other phenols from Glycyrrhiza lepidota. Phytochemistry, 22, 573, 1983. 

Ahsan, M. et al., Novel O-prenylated flavonoids from two varieties of Boronia coerulescens, Phytochemistry, 37, 259, 1994. 

Ngadjui, B.T. et al., Dorsilurins C, D and E, three prenylated flavonoids from the roots of Dorstenia psilurus. Phytochemistry, 52, 731, 1999. 

Fukai, T. et al.. Structures of five new prenylated flavonoids, gancaonins L, M, N, O and P from aerial parts of Glycyrrhiza uralmsis. Heterocycles, 31, 373, 1990. 

Garcez, F.R. et al., Prenylated flavonoids as evolutionary indicators in the genus Dahlstedtia, Phytochemistry, 27, 1079, 1988. 

Kijjoa, A. et al.. Further prenylated flavonoids from Artocarpus elasticus. Phytochemistry, 47, 875, 1998. 

Seo, E.-K. et ak. Bioactive prenylated flavonoids from the stem bark of Artocarpus kemando. Arch. Pharm. Res., 26, 124, 2003. 

Cidade, H.M. et al., Artelastocarpin and carpelastofuran, two new flavones, and cytotoxicities of prenyl flavonoids from Artocarpus elasticus against three cancer cell lines, Planta Med., 67, 867, 2001. 

Sutthivaiyakit, S. et al., Diterpenylated and prenylated flavonoids from Macaranga denticulate. Tetrahedron, 58, 3619, 2002. 

Saxena, V.K. and Singhal, M., Novel prenylated flavonoid from stem of Pithecellobium dulce, Fitoterapia, 70, 98, 1999. 

From a chemosystematic point of view, it is interesting to note that prenylated flavonoids such as microfolione (56) have been found in a species of the family Ptaeroxylaceae, because the relationships of this family with other families were disputed in the past. Most taxonomists considered the Ptaeroxylaceae closely related to families in the order Rutales to which the Rutaceae and Meliaceae belong, whereas others considered it related to the Sapindaceae. Flavonoid chemistry supports a close relationship to the Rutaceae and Meliaceae, as iso-prenylated flavanones also occur in these families, e.g., 58 and 98 in Boronia coerulescens ssp. spinescens, the farnesyl-bearing 121 (Figure 15.3) in B. ramosa (Rutaceae)," and flowerine (59) and flowerone (60) in Azadirachta indica (Meliaceae). Microfolione is one of the few new flavanones for which the (2i )-configuration has been determined. 

Yenesew, A. et al., Two prenylated flavonoids from the stem bark of Erythrina burtii. Phytochemistry, 63, 445, 2003. 

Tahara, S. et al., Prenylated flavonoids in the roots of yellow lupin. Phytochemistry, 36,1261,1994. 

Ngadjui, B.T. et ah, Geranylated and prenylated flavonoids from the twigs of Dorstenia mannii. Phytochemistry, 48, 349, 1998. 

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