Electrocardiographic changes

The adverse reactions associated witii die administration of chloroquine (Aralen HC1 and phosphate) and hydroxychloroquine include hypotension, electrocardiographic changes, visual disturbances, headache, nausea, vomiting, anorexia, diarrhea, and abdominal cramps. 

Adverse reactions associated wiHi administraHon of the xanHiine derivatives include nausea, vomiting, restiess-ness, nervousness, tachycardia, tremors, headache, palpitations, increased respirations, fever, hyperglycemia, and electrocardiographic changes. 

Cardiac-changes in pulse rate or rhythm electrocardiographic changes, such as bradycardia, tachycardia, premature ventricular contractions, bigeminal (two beats followed by a pause), or trigeminal (three beats followed by a pause) pulse. Other arrhythmias (abnormal heart rhythms)also may be seen. 

ADMINISTERING CALCIUM. When calcium is administered IV, the solution is warmed to body temperature immediately before administration, and the drug is administered slowly. In some clinical situations, die primary health care provider may order the patient to have a cardiac monitor because additional drug administration may be determined by electrocardiographic changes. 

Truppman F, Ellenbery J (1979) The major electrocardiographic changes during chemical face peeling. Plast Reconstr Surg 63 44... 

LD isoenzyme abnormality does not precede the appearance of the (mb) in the serum following myocardial infarction. The reappearance of (mb) is interpreted as diagnostic of reinfarction, and correlates with new electrocardiographic changes and an altered clinical course. 

Cardiovascular Worsening hypertension, edema, dyslipi-demia, left ventricular hypertrophy, electrocardiographic changes and chronic heart failure. 

Kosmider S, Petelenz T. 1962. [Electrocardiographic changes in elderly patients with chronic professional lead poisoning]. Pol Arch Med Wewn 32 437-442. (Polish)... 

Currently, orally administered LBH589 is in Phase 11 clinical trials and at lower doses the electrocardiographic change can be abrogated. A Phase 11 study for LBH-589 in soUd and Uquid tumors is ongoing. 

M2. Maclean, D., Griffiths, P. D., and Elmslie-Smith, D., Serum enzymes in relation to electrocardiographic changes in accidental hypothermia. Lancet ii, 1266-1270 (1968). 

Conaway HB, Hoven F. 1946. Electrocardiographic changes in carbon tetrachloride poisoning. U.S. Navy Med Bull 46 593-595. 

The electrocardiographic changes observed after disopyramide administration are identical to those seen with quinidine and procainamide. 

Lidocaine does not usually change the PR, QRS, or QT interval, although the QT may be shortened in some patients. The paucity of electrocardiographic changes reflects lidocaine s lack of effect on healthy myocardium and conducting tissue. 

Amiodarone s predominant electrocardiographic changes include prolongation of the PR and QT intervals, development of U waves, and changes in T-wave contour. 

The most important electrocardiographic change produced by verapamil is prolongation of the PR interval, a response consistent with the known effects of the drug on A-V nodal transmission. Verapamil has no effect on intraatrial and intraventricular conduction. The predominant electrophysiological effect is on A-V conduction proximal to the His bundle. 

Prolonged therapy may result in peripheral neuritis, neuromyopathy, hypotension, electrocardiographic changes, agranulocytosis, aplastic anemia, thrombocytopenia, seizures, and psychosis. 

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