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Precautions side effects

Does the resource cover the following information indication, mechanism of action, contraindications/precautions, side effects, drug interactions, and dose ... [Pg.741]

Compared with monotherapy, combination therapy is relatively unstudied in terms of the effects on CHD event reduction and may reduce patient compliance through increased side effects and increased costs. When used appropriately and with proper precautions, however, they are effective in normalizing lipid abnormalities, particularly in patients who cannot tolerate adequate doses of statin therapy for more severe forms of dyslipidemia. [Pg.192]

Lenalidomide was approved recently for the indication of myelodysplastic syndrome where the 5q deletion is present. Since lenalidomide is an analog of thalidomide, all the same precautions must be taken to prevent phocomelia. The time to maximum lenalidomide concentrations occurs 0.5 to 4 hours after the dose. The terminal half-life ranges from 3 to 9 hours. Approximately 65% of lenalidomide is eliminated unchanged in the urine, with clearance exceeding the glomerular filtration rate. To date, no pharmacokinetic studies have been done in patients with renal dysfunction. Lenalidomide is used in the treatment of myelodysplastic syndrome and multiple myeloma. Other side effects are neutropenia, thrombocytopenia, deep vein thrombosis, and pulmonary embolus. [Pg.1293]

With all forms of drugs there are side effects and precautions. The pharmacist and veterinarian are responsible for passing any such information on to clients. [Pg.728]

Garlic s proven mechanisms of action include (a) inhibition of platelet function, (b) increased levels of two antioxidant enzymes, catalase and glutathione peroxidase, and (c) inhibition of thiol enzymes such as coenzyme A and HMG coenzyme A reductase. Garlic s anti-hyperlipidemic effects are believed to be in part due to the HMG coenzyme A reductase inhibition since prescription medications for hyperlipidemia have that mechanism of action (statins). It is unknown whether garlic would have the same drug interactions, side effects, and need for precautions as the statins. [Pg.738]

Some precautions are based on the dietary supplement s side effect profile. St. John s wort may induce photosensitivity therefore, fair-skinned persons should be cautioned about exposure to bright sunlight while taking the herb. [Pg.738]

Since halcinonide is a corticosteroid, large doses of unformulated steroid are needed systemically before the unwanted side effects appear. Halcinonide is usually formulated at concentrations of 0.1%, or less. Normal handling precautions are adequate. [Pg.253]

CDC, Update vaccine side effects, adverse reactions, contraindications, and precautions reommendations of the advisory committee on immunization practices (ACIP), MMWR, 45(RR12 001), September 6,1996. [Pg.518]

Indications, contraindications, warnings, precautions and side effects... [Pg.373]

It is fair to say that dialogue needs to continue between the Agency and the pharmaceutical industry regarding the terminology that the requirement of ALL contraindications, warnings, precautions and side-effects will mandate and its usefulness in informing patients. The question of roll-up warnings remains a subject for discussion, as does a debate about the difference between adverse events and adverse reactions. [Pg.373]

The information specified above in relation to dosage, method of use, side effects, precautions and contra-indications and any warning which is required to be included in advertisements, must be placed in such a position in the advertisement, that its relationship to the claims and indications for the product can be appreciated by the reader. [Pg.738]

The regulation of Na+ ions and channels are the means for possible correction of abnormalities in tissue functioning and ganglic integrations. However, it is necessary to pay attention to the possible unwanted side effects. Alkaloids are complex agents. Smaller doses are safer when considering cell toxicity or other possible metabolic effects. Alkaloids and alkaloidal substances should be given serious consideration and precautions before use. [Pg.185]

Magnesium sulfate, applied intravenously is often used as tocolytic. The mechanism of action is not completely clear but might involve a competition with calcium on the cellular level. Precautions in the sense of magnesium plasma level monitoring must be taken in patients with renal insufficiency since this divalent kation is eliminated by the kidneys. Relatively high plasma concentrations are necessary to achieve a sufficient tocolysis. The relatively frequent side effects are respiratory depression, depressed reflexes, headaches, palpitation and skin flushing in the mother and muscle relaxation and, rarely, CNS depression in the fetus. [Pg.306]

Terbutaline is frequently used in the management of premature labor, although it has not been marketed for such use. Its effectiveness, side effects, precautions, and contraindications are similar to those of all P2-adrener-gic agonists. Terbutaline can cause tachycardia, hypotension, hyperglycemia, and hypokalemia. It can be given orally in addition to subcutaneous or intravenous administration. [Pg.720]

Side-effects Etorphine induces potent CNS depression with impairment of respiration leading to coma and death in higher doses. Because of its rapid penetration through skin and mucosa and its outstanding potency, special precautions are necessary to avoid contamination during... [Pg.190]

In a recent personal evaluation of side effects related to SLIT in 354 children suffering from allergic asthma and followed for at least 39 months no adverse event was observed in 90.4% of the children [61]. We observed 0.155 mild to moderate reactions per 1,000 administrations. In 15 episodes only dosage adjustment was required. In 5 children IT was stopped as a precaution. No anaphylactic reaction or multiple-organ life-threatening event occurred [61]. [Pg.84]

Discusses serious side effects that may occur. Precautions... [Pg.11]

Objective 2 entails the assessment of a new drug to determine what types of clinical side effects can be expected and in which patient populations, at what doses and dose durations, and whether the side effects are reversible and, if so, after how long. This knowledge is summarized in the Integrated Summary of Safety (ISS) portion of the NDA/BLA submission and is used by regulatory authorities to decide what should be included in the precautions or warnings sections of the drug label. [Pg.506]

The application for a licence for general use (marketing application) should include a draft Summary of Product Characteristics for prescribers. A Patient Information Leaflet must be submitted. These should include information on the form of the product (e.g. tablet, capsule, sustained-release, liquid), its uses, dosage (adults, children, elderly where appropriate), contraindications (strong recommendation), warnings and precautions (less strong), side-effects/ adverse reactions, overdose and how to treat it. [Pg.57]

What precautions may be taken to avoid some of these side effects ... [Pg.156]

Part three deals with the different classes of psychopharmaceuticals, including dosage and choice of medication, side effects, and mechanism of action (where and in so far as it has been established). Also covered are precautions for monitoring medication effects and serum levels, and guidelines for educating patients and their families about the effects and side effects of these drugs. [Pg.144]


See other pages where Precautions side effects is mentioned: [Pg.270]    [Pg.205]    [Pg.270]    [Pg.205]    [Pg.235]    [Pg.550]    [Pg.626]    [Pg.812]    [Pg.72]    [Pg.54]    [Pg.395]    [Pg.79]    [Pg.737]    [Pg.441]    [Pg.130]    [Pg.324]    [Pg.160]    [Pg.151]    [Pg.54]    [Pg.250]    [Pg.450]    [Pg.1265]    [Pg.538]    [Pg.385]    [Pg.509]    [Pg.573]    [Pg.3990]    [Pg.28]   
See also in sourсe #XX -- [ Pg.122 , Pg.123 , Pg.124 ]




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