Potassium iodide, saturated solution

An additional example for ion pair extraction of QTA (ipratropium) was described by Tang et al. mixing equine urine with alkaline saturated borax buffer prior to extraction with EE allowing to remove more lipophilic compounds. Subsequently, the EE layer was discarded and an alkaline potassium iodide-glycine solution was added to the aqueous phase. Afterwards, the ipratropium-ion pair complex was extracted twice with dichloromethane yielding in a recovery of 82 % [24] (Table 3). 

Iodine Solution. Cold saturated aqueous solution. (If a more concentrated solution is required, add i g. of powdered iodine to a solution of 2 g. of potassium iodide in a minimum of water, and dilute the solution to 100 ml.)... 

In a 500 ml. three-necked flask, equipped with a thermometer, a sealed Hershberg stirrer and a reflux condenser, place 32-5 g. of phosphoric oxide and add 115-5 g. (67-5 ml.) of 85 per cent, orthophosphoric acid (1). When the stirred mixture has cooled to room temperature, introduce 166 g. of potassium iodide and 22-5 g. of redistilled 1 4-butanediol (b.p. 228-230° or 133-135°/18 mm.). Heat the mixture with stirring at 100-120° for 4 hours. Cool the stirred mixture to room temperature and add 75 ml. of water and 125 ml. of ether. Separate the ethereal layer, decolourise it by shaking with 25 ml. of 10 per cent, sodium thiosulphate solution, wash with 100 ml. of cold, saturated sodium chloride solution, and dry with anhydrous magnesium sulphate. Remove the ether by flash distillation (Section 11,13 compare Fig. II, 13, 4) on a steam bath and distil the residue from a Claisen flask with fractionating side arm under diminished pressure. Collect the 1 4-diiodobutane at 110°/6 mm. the yield is 65 g. 

Potassium Iodide. When potassium iodide [7681-11-0] is adrninistered orally for several (6—8) weeks, a therapeutic effect may be obtained ia the subcutaneous form of sporotrichosis. Amphotericin B is used iatravenously to treat systemic sporotrichosis. The KI dosage is usually a saturated solution ia water (1 g/mL). The usual oral dose is 30 mg/kg/d. Children should receive five droplets, three times a day (after meals) the dose may be iacreased to 15—20 droplets. Side effects iaclude digestive disorders, swelling of the saUvary glands, and lacrimation. Thyroid function tests may be disturbed. 

A solution of 0.46 g of the diazoketone in 100 ml of chloroform is shaken with 22 ml of 48 % hydriodic acid for 1.5 min. After the addition of 400 ml of chloroform, the organic layer is washed successively with a saturated solution of potassium iodide, with a solution of sodium thiosulfate and with water. After drying, evaporation of the solvent yields 0.44 g of a product which is chromatographed over 10 g of alumina (diam. of column 1.0 cm). Elution with benzene (400 ml) and benzene-ether (9 1) (200 ml) gives 0.32 g of 3jS,5) ,19-trihydroxypregnan-20-one 3,19-diacetate (yield 76%) mp 96-99°. 

Place the prepared copper acetate solution in the beaker and add 10 mL of 20 per cent potassium iodide solution. Set the stirrer in motion and add distilled water, if necessary, until the platinum plate electrode is fully immersed. Use a saturated calomel reference electrode, and carry out the normal potentiometric titration procedure using a standard sodium thiosulphate solution as titrant. 

Procedure. Dissolve a suitable weight of the sample of lead in 6M nitric acid add a little 50 per cent aqueous tartaric acid to clear the solution if antimony or tin is present. Cool, transfer to a separatory funnel, and dilute to about 25 mL. Add concentrated ammonia solution to the point where the slight precipitate will no longer dissolve on shaking, then adjust the pH to 1, using nitric acid or ammonia solution. Add 1 mL freshly prepared 1 per cent cupferron solution, mix, and extract with 5 mL chloroform. Separate the chloroform layer, and repeat the extraction twice with 1 mL portions of cupferron solution + 5 mL of chloroform. Wash the combined chloroform extracts with 5mL of water. Extract the bismuth from the chloroform by shaking with two 10 mL portions of 1M sulphuric acid. Run the sulphuric acid solution into a 25 mL graduated flask. Add 3 drops saturated sulphur dioxide solution and 4 mL of 20 per cent aqueous potassium iodide. Dilute to volume and measure the transmission at 460 nm. 

Alternative—saturated solution of potassium iodide (SSKI) 5-10 drops in water q8h... 

Large doses of iodide inhibit the synthesis and release of thyroid hormones. Serum T4 levels may be reduced within 24 hours, and the effects may last for 2 to 3 weeks. Iodides are used most commonly in Graves disease patients prior to surgery and to quickly reduce hormone release in patients with thyroid storm. Potassium iodide is administered either as a saturated solution (SSKI) that contains 38 mg iodide per drop or as Lugol s solution, which contains 6.3 mg iodide per drop. The typical starting dose is 120 to 400 mg/day. Iodide therapy should start 7 to 14 days prior to surgery. Iodide should not be... 

SSKI Saturated solution of potassium iodide VO Verbal order... 

Potassium iodide is available as a saturated solution (SSKI, 38 mg iodide per drop) or as Lugol s solution, containing 6.3 mg of iodide per drop. 

These 3 1. of distillate are then mixed with the first yield of quinoline and 280 g. (150 cc.) of concentrated sulfuric acid are added. The solution is cooled to 0-50, and a saturated solution of sodium nitrite added until a distinct excess of nitrous acid is present (as shown either by starch-potassium iodide paper or by the odor). This generally requires 50 to 70 g. of sodium nitrite. The mixture is then warmed on a steam bath for an hour, or until active evolution of gas ceases, and is then distilled with steam until all the volatile material has been expelled (4 1. of... 

Materials Required Thyroid gland dried 1.0 g anhydrous potassium carbonate 17.0 g bromine solution (9.6 ml of Br2 and 30 g of KBr in 100 ml DW) 7.0 ml dilute phosphoric acid (10% w/v) 42.0 ml starch iodide paper phenol solution (saturated solution of phenol in water) 5.0 ml potassium iodide solution (10% w/v in water) 0.01 N sodium thiosulphate solution starch solution. 

Tetrahydrofuran (36 g., 0.5 mole) (Note 1) is added to a mixture of potassium iodide (332 g., 2 moles), 85% orthophosphoric acid (231 g., 135 ml., 2 moles), and phosphoric anhydride (65 g.) (Notes 2, 3, and 4) in a 1-1. three-necked flask equipped with a sealed mechanical stirrer, a reflux condenser, and a thermometer. The mixture is stirred and heated at its reflux temperature for 3 hours, during which time a dense oil separates from the acid layer. The stirred mixture is cooled to room temperature, and 150 ml. of water and 250 ml. of diethyl ether are added (Note 5). The ether layer is separated, decolorized with dilute aqueous sodium thiosulfate solution, washed with cold saturated sodium chloride solution, and dried over anhydrous sodium sulfate. The ether is removed by distillation on a steam bath, and the residue is distilled under reduced pressure from a modified Claisen flask. The portion boiling at 108-110°/10 mm. is collected. The yield of colorless 1,4-diiodobutane ( o 1-615 df 2.300) (Note 6) is 143-149 g. (92-96%). 

Tetrammino-cupric Iodide is produced by adding potassium-iodide solution to an aqueous ammoniacal solution of cupric sulphate and then saturating the mixture with ammonia gas at 0° C.3... 

Pyridino-bismuth Iodide, [Bi(CsHsN)]I3, is formed by treating a eold mixture of bismuth trichloride in pyridine with potassium iodide, when the pyridino-iodide separates as a dark red powder.1 The substance is soluble in alcohol and in aqueous potassium iodide, and separates from a saturated solution in red needle-shaped crystals which decompose on heating. The corresponding quinoline derivative, [Bi(C9H7N)]I3, is also a red crystalline substance, and is produced by boiling quinolino-. bismuth chloride with an aqueous solution of potassium iodide. 

Dihydroxo-diaquo-diammino-chromic Chloride, [Cr(NH3), (H20)2(OH)2]Cl, is formed by the addition of ammonia or pyridine to an aqueous solution of tetraquo-diammino-chloride, or saturating an aqueous acetic acid solution with rubidium chloride. It forms light red violet crystals which are insoluble in water. The iodide is obtained from the bromide on addition of potassium iodide to a dilute acetic acid solution of the salt as a light red violet precipitate. The thiocyanate, [Cr(NH3)2(H20)2(OH)2]SCN, is amorphous, and is prepared from the bromide by dissolving in aqueous acetic acid and adding potassium thiocyanate. 

Active oxygen content is determined iodometrically 3 In an iodine flask, an accurately weighed sample (0.1-0.3 g.) is dissolved in 20 ml. of an acetic acid-chloroform solution (3 2 by volume), and 2 ml. of saturated aqueous potassium iodide solution is added. The flask is immediately flushed with nitrogen, stoppered, and allowed to stand at room temperature for 15 minutes. Fifty milliliters of water is then added with good mixing, and the liberated iodine is titrated with 0.1 A sodium thiosulfate, employing starch as indicator. A blank titration, which usually does not exceed 0.2 ml., is also run. One milliliter of 0.1 N sodium thiosulfate is equivalent to 0.00821 g. of tetralin hydroperoxide. 

Iodometric titration was carried out as shown below About 100 mg. of hydroxylamine-O-sulfonic acid was exactly weighed and dissolved in 20 ml. of distilled water. Sulfuric acid (10 ml. of 10% solution) and 1 ml. of saturated potassium iodide solution were then added. After the solution was allowed to stand for 1 hour, liberated iodine was titrated with 0.1 N sodium thiosulfate solution until the iodine color disappeared. The following stoichiometric relation was used 0.1 N Na2S203 (1 ml.) = 5.66 mg. H3NOSO3. Hydroxylamine-O-sulfonic acid should be stored in tightly sealed bottles in a refrigerator. 

Pour 5 ml of a saturated potassium iodide solution into a test tube. Pass a stream of chlorine through the solution. What substance evolves Filter the substance on a smooth filter and dry it in the air. What impurity will the iodine contain How can it be purified ... 

Leave one test tube for comparison, add a saturated potassium iodide solution to the second tube, and vigorously shake it. What happens The formation of what substance explains the increase in the solubility of iodine Write the equation of the reaction. 

Blackpowder containing silver iodide is obtained by saturating the blackpowder with an acetone solution of potassium silver iodide and then drying it. The required solution is prepared by dissolving 15 g of potassium iodide and 50 g of silver iodide in 200 g of acetone. 

To Fix and Finish tie Picture.—When the plate has been well washed after the development, by pouring water over it from a jug, the yellow iodide of silver should ho dissolved out by means of either a saturated solution of hyposulphite of soda, or a solution of cyanide of potassium—strength about five grains to the ounce of water. This should be poured over the plate, and should be allowed to run backwards and forwards over it until the whole of the yellow iodide of silver in the plato has disappeared aftor which it should bo thoroughly well washed, by pouring water over it from a jug, and sot up to drain and dry or it may be dried before a fire. It is then ready to bo varnished,... 

Method I (4). Sample was quenched with a solution of 50 ml. acetic acid and 2.5 ml. saturated aqueous potassium iodide. 

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