Potassium iodate toxicity

MERCURIC THIOCYANATE (592-85-8) Hg(SCN)i Moderately unstable solid. Possible violent reaction with strong oxidizers strong acids organic peroxides, peroxides and hydroperoxides potassium chlorate potassium iodate, silver nitrate, sodium chlorate, nitric acid. Incompatible with ammonia, chlorates, hydrozoic acid, methyl isocyanoacetate, nitrates, nitrites, perchlorates, sodium peroxyborate, trinitrobenzoic acid, urea nitrate. When heated, this material swells to many times its original bulk. Attacks aluminum in the presence of moisture. Decomposes above 329°F/165°C, releasing toxic mercury and cyanide fumes, and sulfur and nitrogen oxides. On small fires, use dry chemical powder (such as Purple-K-Powder), alcohol-resistant foam, or COj extinguishers. MERCURIC (Spanish) (7439-97-6) see mercury. 

SODIUM RHODANIDE (540-72-7) NaSCN Exposure to light causes slow decomposition, forming cyanide, sulfur oxides, and nitrous vapors. Violent reaction, possibly explosion, with strong oxidizers, organic peroxides, nitric acid. Incompatible with acids, bases, chlorates, anunonia, amines, amides, alcohols, glycols, caprolactam, nitrates, peroxides and hydroperoxides, potassium chlorate, potassium iodate, silver nitrate, sodium chlorate. Contact with sulfuric acid forms toxic carbonyl sulfide gas. Forms explosive mixture with sodium nitrate. Thermal decomposition releases oxides of sulfur and nitrogen. 

Potassium iodate, KIO3, the most thermodynamically stable and naturally occurring compound of polyvalent iodine, has found some application as a dietary supplement and a food additive. It can be used as a source of iodine in iodized salt and also as a dough conditioner [3]. In fact, because potassium iodate is more stable than iodide in the presence of air, most health authorities preferentially recommend iodate as an additive to salt for correcting iodine deficiency. Iodate is rapidly reduced to iodide in the body iodide is essential for thyroid function. However, high levels of iodate (0.600 mg per day) have been shown to cause damage to the retina, resulting in ocular toxicity [4]. The recommended level of iodine in iodized salt is between 20 and... 

Radioiodine is produced from uranium and plutonium during the process of fission. Although it makes up only 1-2% of fission products, once absorbed it concentrates in the thyroid where it increases the risk of thyroid cancer, especially in children. Stable iodine in the form of potassium iodate tablets can be used to saturate the thyroid and prevent toxic build-up of the radioactive isotope. As a consequence, those exposed should receive potassium iodate as soon as possible after exposure (recommended doses adult 170 mg, child under 3 years 42.5 mg, child 3-12 years 85 mg). 

EXPLOSION and FIRE CONCERNS flammable in the form of dust when exposed to heat or flame when heated or on contact with acid or acid fumes, it emits highly toxic fumes dangerous when water solutions of arsenicals are in contact with active metals such as iron, zinc, aluminum flammable by chemical reaction with bromates, chlorates, iodates, peroxides, lithium, silver nitrate, nitric acid, potassium permanganate, chromium trioxide, chlorine trifluoride, chlorine oxide, bromine trifluoride, bromine pentafluoride, bromine azide use foam, carbon dioxide, or dry chemical for firefighting purposes.. 

Iodine is introduced into the body mostly through food, iodized salt, and also drinking water and milk. Dietary iodine is found in the form of iodide or iodate of potassium, calcium, or sodium (Venkatesh and Dunn, 1995). When iodine requirements are not met, the production of thyroid hormones is reduced and the thyroid gland enlarges to compensate for this reduction. In adults, mild iodine deficiency is associated with nontoxic nodular goiter and, less often, with toxic nodular goiter because the constitutive (thyrotropin-independent) growth and the functional potential of some clones of thyroid cells increase. 

---