Polyvinylpyrrolidone applications

Yamakoshi Y, Yagami T, Fukuhara K, et al. (1994) Solubilisation of fullerenes into water with polyvinylpyrrolidone applicable to biological test. J Chem Soc Chem Commun. 4 517-518. 

Toxic degradation products this effect is applicable to biodegradable polymers for example, degradation of poly(alkylcyanoacrylate) leads to the formation of formaldehyde which is considered toxic in humans. In the case of a bioerodible polyvinylpyrrolidone), the accumulation of the dissolved polymer in the liver raises a longterm toxicity issue. 

Wessel W, Schoog M, Winkler E. Polyvinylpyrrolidone (PVP), its diagnostic, therapeutic and technical application and consequences thereof. Arzneimittelforschung 1971 21 1468-1482. 

Polyvinylpyrrolidone (PVP) is a synthetic polymer derived from the Reppe chemistry and is widely used in the pharmaceutical, personal care, cosmetic, agriculture, beverage, and many industrial applications. PVP is a polar and amorphous polymer which is soluble in water and some organic solvents, such as alcohols, chlorinated hydrocarbons, dimethyl formamide, dimethyl acetamide, and V-methyl pyrrolidone. 

Insoluble polyvinylpyrrolidone finds extensive applications in the pharmaceutical and beverage industries as a swelling popcorn polymer with selective adsorp-... 

While there are no such lists for pharmaceutical products, various countries have positive lists regulating the use of auxiliaries in food. These lists include soluble and insoluble polyvinylpyrrolidone, though in some cases only for certain applications. 

In 1987 the World Health Organization (WHO + FAO) specified an Accepted Daily Intake (ADI) value for soluble polyvinylpyrrolidone (povidone) in food of 0-50 mg/kg body weight [372]. For Crospovidone the ADI value is not specified and therefore no limit is given for the application in foods [215]. 

High-molecular mass surfactants such as butyl acrylate-butyl methacrylate-methacrylic acid copolymer sodium salts, starburst dendrimers, poly(amidoamines), and diaminobutane-based poly(propyleneimine) as well as cationic polyelectrolytes (ionenes) had all been presented as successful secondary phases for aromatic compounds. The determination of 10 nitrophenols in glycine buffers modified by 3-CD (0-10 mmolL" ) and polyvinylpyrrolidone (PVP) (0.5-2.5% w/v) is an example of application of polymer-based electrolytes to rain, tap, and process water. ... 

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