Polyurethane scaffolds mechanical properties

Yeganegi M, Kandel RA, Santerre JP (2010) Characterization of a biodegradable electrospun polyurethane nanofiber scaffold mechanical properties and cytotoxicity. Acta Biomater 6(10) 3847-3855... 

Furthermore, meshes have been composed of multilayers consisting of different polymers. Matsuda and coworkers produced bilayer meshes of a thick polyurethane microfiber mesh and a thin nanofiber mesh composed of type I collagen. The material decouples mechanical properties from the biochemical functionality of collagen to form a prototype scaffold for artificial grafts [194],... 

Fig. 6 Cell alignment and ECM production on polyurethane films (top), aligned nanofibers middle), and randomly oriented nanofibers (bottom) (a). Cell proliferation (b), collagen I production (c), and mechanical properties (d) of aligned and randomly oriented scaffolds [115]...

Mi H-Y, et al. Morphology, mechanical properties, and mineralization of rigid thermoplastic polyurethane/hydroxyapatite scaffolds for bone tissue applications effects of fabrication approaches and hydroxyapatite size. J Mater Sci 2014 49(5) 2324-37. 

Emerging work on new polyurethane scaffolds aims to enhance osteoconductivity and mechanical properties using novel methods and additives. Ionic liquids have been proposed to add antibacterial properties to polyurethanes while improving mechanical properties and increasing hydrophilicity. l-bntyl-3-methylimidazolium hexafluorophosphate ionic Uqnid blended with a thermoplastic polyurethane improved the electrospun fiber morphology and non woven mats exhibited 99.9% antibacterial efficiency against Escherichia coli and Staphylococcus aureus [78]. 

Mi, H.Y, Jing, X., Salick, M.R., Cordie, T.M., Peng, X.F., Turng, L.S., 2014. Morphology, mechanical properties, and mineralization of rigid thermoplastic polyurethane/hydroxyap-atite scaffolds for bone tissue applications effects of fabrication approaches and hydroxyapatite size. Journal of Materials Science 49, 2324-2337. http //dx.doi.org/10.1007/ S10853-013-7931-3. 

Cell proliferation and differentiation Cell-seeded fibrons scaffold was fabricated via electtospinning/ electrospraying method, and scaffold mechanical and stmctural properties were controlled by polymer solntion pumping speed and polyurethane/hydrogel ratio. CDC cardiac differentiation was successfully achieved in scaffolds with high fiber volume fraction and small scaffold modulus at small strains. Xu et al. Mechanical/morphology/ composition... 

Amoroso NJ, D Amore A, Hong Y, Wagner WR, Sacks MS. Elastomeric electrospun polyurethane scaffolds the interrelationship between fabrication conditions, fiber topology, and mechanical properties. Adv Mater 2011 23 106-11. 

Guelcher SA, Gallagher KM, Srinivasan A, McBride SB, Didier JE, Doctor JS, et al. Synthesis, in vitro biocompatibUity and biodegradation, and mechanical properties of two-component polyurethane scaffolds effects of water and polyol composition. Tissue Eng 2007 13(9) 2321-33. 

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