Poly neural stimulation applications

At present a few studies of nanofibers and nanombes are focused on CNS drug delivery. One study evaluated electrospun nanofibers of a degradable polymer, PLGA, loaded with antiinflammatory agent, dexamethasone, for neural prosthetic applications (Abidian and Martin, 2005). A conducting polymer, poly(3,4-ethylenedioxythiophene), was deposited to the nano-fiber surface and the coated nanofibers were then mounted on the microfabricated neural microelectrodes, which were implanted into brain. The drug was released by electrical stimulation that induced a local dilation of the coat and increased permeability. 

---