Platinum complexes Schiff bases

Novel platinum(ii) Schiff base complexes were found to be efficient photosensitizers for H2 evolution from mixed solvents (e.g. DMF/H2O) under visible light irradiation, with a cobalt complex as catalyst and TEA as sacrificial electron donor. Catal5Aic activity is influenced by the presence of substituents on the ligand electron-withdrawing groups, in particular, have a positive effect. ... 

Ramirez et al.106 have investigated the series of platinum complexes of chiral Schiff bases [43]. 

Although complexes with these ligands are common in palladium(II) chemistry, their occurrence is more scarce in platinum(II) compounds. Nevertheless these complexes can be prepared, examples being platinum(II) complexes of the optically active quadridentate Schiff base of salicylaldehyde and (R)-l, 2-diamines.1212 An alternative synthesis involves formation of the Schiff base by reaction of a complexed amino ligand on platinum(II) with amide acetates (equation 372).1213... 

Schiff bases -alkanolamines [ALKANOLAMINES - ALKANOLAMINESFROM OLEFIN OXIDES AND AMMONIA] (Vol 2) -from benzaldehyde [BENZALDEHYDE] (Vol 4) -platinum-group metal complexes of [PLATINUM-GROUP METALS, COMPOUNDS] (Vol 19)... 

Originally devised as a method for the conversion of amino acids or amino acid esters to aldehydes. The Akabori reaction has been modihed for use in the determination of C-terminal amino acids by performing the reaction in the presence of hydrazine and for the production of derivatives useful for mass spectrometric identihcation. See Ambach, E. and Beck, W., Metal-complexes with biologically important ligands. 35. Nickel, cobalt, palladium, and platinum complexes with Schiff-bases of... 

Although there has been a great deal of research concerning how plahnum(II) complexes bind to biological molecules and the hkely mechanism of antitumor activity of these platinum-containing species, far less attention has been paid to the properties of other metal complexes in this arena. Recent attention has fallen on cobalt(II)-Schiff base complexes, as several have been discovered to have promise as antiviral agents. A review of recent work has appeared elsewhere [64], so the topic will not be covered here however, in addition to focusing on recent developments, emphasis is placed on the introduction of the new head unit, 3,6-diformylpyridazine (13), into Schiff-base macrocyclic electrochemistry. 

R 102 M.R. Bermejo, A.M. Garda-Deibe, A.M. Gonzalez, O.L. Hoyos, M. Maneiro and M. Rey, The Diversity Observed in Manganese(III)- Schiff Base Complexes Models for a Variety of Biological Systems , p. 61 R 103 L.M. Mink and R.K. Boggess, Platinum(II) and Platinum(IV) Tetra-phenylporphyrin Complexes Synthesis, Characterization, and Electrochemistry , p. 125... 

PAMAM GO Schiff base drug complex Chloropyridylimine- platinum(ll) Chloropyridylimine- copper(ll) Schiff base Pt complex Cancer n.a. Yes No 324... 

The use of metal chelates of five tetradentate 8-ketoamine Schiff bases derived from DL-stilbenediamine and meso-stilbenediamines has been assessed for the separation of Cu(II), Ni(II), Pd(II), and oxovanadium(IV) by capillary column gas chromatography with flame ionization (FID) or microwave-induced plasma atomic emission detection [532]. The linear response for the metal chelates of bis(acetylpivalylmethane)-DL-stilbenediimine was found to extend from 0.86-8.6 ng of complex. For the detection of platinum with microwave-induced plasma atomic emission, the volatile Pt(II) complex of N,N-ethylene-bis(5,5-dimethyl-4-oxohexane-2-imine) can be quantitatively eluted from a GC capillary column [533]. 

The increase in electrophilicity of coordinated ligands commonly leads to more favorable hydrolysis reactions. There are many reports on hydrolysis reactions of coordinated carboxamides, halogenated alkylamines, Schiff bases, thioamides, nitriles, etc. For example, thiourea and thioacetamide complexes of platinum metals decompose on heating in basic solution with formation of the corresponding metal sulfides, Eq. 1.26 and 1.27 ... 

Demetgiil C, Deletioglu D, Karaca F, Yalfinkaya S, Timur M, Serin S (2010) Synthesis and characterization of a Schiff base derived from 2-aminobenzylamine and its Cu(II) complex electropolymerization of the complex on a platinum electrode. J Coord Chem 63 (12) 2181-2191. doi 10.1080/00958972.2010.496852... 

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