Plantago ovata, seeds

Cervical dilator. Isaptent, prepared from granulated Plantago ovata seed husk, administered as a cervical dilator to 804 women between 15 and 45 years of age, achieved satisfactory dilatation in 94% of the cases. The cervical dilatation bore no relationship to age, parity, and gestation period of the subjects. There was no apparent damage to the cervix, and the vaginal flora remained unchanged in the randomly selected subjects . 

PO008 Nordgaard, I., H. Hove, M. R. Clausen, and P. B. Mortensen. Colonic production of butyrate in patients with previous colonic cancer during long-term treatment with dietary fiber (Plantago ovata seeds). Scand J Gastroenterol 1996 31(10) 1011-1020. 

The effect of a Plantago ovata seed containing preparation of appetite vari- PO055 ables, nutrient, and energy intake. Int... 

Jamal, S., 1. Ahmad, R. Agarwal, M. Ahamad, and S. M. Osman. A novel 0X0 fatty acid in Plantago ovata seed oil. Phytochemistry 1987 26(11) 3067-3069. 

PO097 Leng Peschlow, E. Plantago ovata seeds as dietary fiber supplement physiologi-cal and metabolic effects in rats. Br J Nutr 1991 66(2) 331-349. 

Linum usitatissimum (seed) Plantago arenaria (seed, seed husk) Plantago asiatica (seed, seed husk) Plantago ovata (seed, seed husk)... 

Psyllium Seed Gum. PsyUium seed gum [8036-16-9] is derived from plants of the genus Plantago several species of which are used as commercial sources. However, most current production is from Plantago ovata grown in India. The gum is located in the coat which is removed by cracking. The gum is then extracted with boiling water and separated from the insoluble residue by filtration. It consists of mixtures of both neutral and acidic polysaccharides, the composition of which is species dependent (66). 

The effect of X -rich ground husks form the seeds of Plantago ovata (is-abgol) on the bread-making properties of various flours was studied with... 

Nakamura, Y., Yoshikawa, N., Hiroki, L, Sato, K., Ohtsuki, K., Chang, C. C., Upham, B. L., and Trosko, J. E. (2005). P-Sitosterol from psyllium seed husk (Plantago ovata Forsk)... 

Romero, A. L., West, K. L., Zern, T., and Eemandez, M. L. (2002). The seeds from Plantago ovata lower plasma lipids by altering hepatic and bile acid metabolism in guinea pigs. /. Nutr. 132, 1194-1198. 

Hypolipidemic activity. Seed hull, administered to mice at a dose of 2.5% of diet for 18 weeks, was inactive " . The husk, administered orally to male Hartley guinea pigs at doses of 7.5 or 10 g/100 g of Plantago ovata for 4 weeks, exerted a hypolipidemic effect by affecting bile acid absorption and altering hepatic cholesterol metabolism Insulin release inhibition. Seed administered orally to 18 patients with noninsulin-dependent diabetes at a dose of 13.6 g/day lowered insulin levels by 17% . 

P0002 Wattiez, N., and M. Hans. A holoside extracted from the seeds of Plantago major L. and Plantago ovata Forsk (P. isphagulata Roxb.). Bull Acad Roy MedBelg 1943 8 386-396. 

PO007 Gelissen, C., B. Brodie, and M. A. Eastwood. Effect of Plantago ovata (psyllium) husk and seeds on sterol metabolism studies in normal and ileostomy subjects, Amer J Clin Nutr 1994 59(2) 395-400. 

PO062 Patel, R. B., C. G. Rana, M. R. Patel, PO073 H. K. Dhyani, and H. V. Chauhan. Chromatographic screening of proteins of seeds of Plantago ovata Forsk. Indian Drugs Pharm Ind 1981 16 3-5. 

Atal, C. K., K. K. Kapoor, and H. H. Siddiqui. Studies on Indian seed oils. Part I. Preliminary screening of li-noleic acid rich oils. Indian J Pharmacy 1964 26 163-164-Siddiqui, H. H., K. K. Kapoor, and C. K. Atal. Studies on Indian seed oils. Part II. Effect of Plantago ovata embryo oil on raised serum cholesterol levels in rabbits. Indian J Pharmacy 1964 26 1663-1664. 

Wasicky, B. Investigations of the seeds of Plantago ovata, P. psyllium, and P. major variety cruenta as laxatives. 

Rutinoside-3 -apioside Plantago ovata and P. psyllium seeds Plantaginaceae 327... 

Nishibe, S., Kodama, A., and Noguchi, Y., Phenolic compounds from seeds of Plantago ovata and P. syllium, Nat. Med. (Tokyo, Japan), 55, 258, 2001. 

Psyllium Hydrophilic Mucciloid. Metamucil, or psyllium hydrophilic mucciloid, is a white-to-cream colored, slighdy granular powder having litde or no odor and a slightly acidic taste. It is made from the mucilaginous portion, ie, outer epidermis, of blond psyllium seeds (Plantago ovata). 

Short-chain fatty acids, especially butyrate, are a preferred source of energy for the colonic epithelium. There is evidence to suggest that butyrate enemas are effective in the treatment of ulcerative cohtis. The seeds of Plantago ovata (a source of fermentable dietary fiber) increase fecal concentrations of butyrate and acetate. In a randomized, open, parallel-group, multicenter study in 105 patients with ulcerative cohtis, P. ovata seeds 10 mg bd were as effective as mesalazine 500 mg tds in maintaining remission over 12 months (10). Adverse effects were similar in the two groups, and included constipation, flatulence, nausea, and diarrhea. 

Plantago seeds are widely used as bulk laxatives under the names of psyUinm (from Plantago psyllium or Plantago indica) and ispaghnla (from Plantago ovata). 

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