Pigment cell tumors

All patients with anterior uveitis should undergo dilated funduscopy. Such examination should be attempted on the initial visit, although it may be difficult because of patient discomfort and/or posterior synechia. In such cases, ophthalmoscopy on the first follow-up visit may yield more useful information. Without adequate careful examination of the peripheral fundus and posterior pole, one cannot rule out the possibility of posterior involvement or masquerade syndromes. Masquerade syndromes are disorders that present as uveitis but do not have an inflammatory etiology. Such diseases either cause a secondary uveitis or are mistaken for a primary uveitis, because of the presence of white cells, red blood cells, pigment, or tumor cells. Examples of masquerade syndromes may include lymphoma, leukemia, retinoblastoma, malignant choroidal melanoma, retinal detachment, and intraocular foreign body. 

Ostrander, G.K., W.E. Hawkins, R.L. Kuehn, A.D. Jacobs, K.D. Berli and J. Pigg. Pigmented subcutaneous spindle cell tumors in native gizzard shad (Dorosoma cepedianum). Carcinogenesis 16 1529-1535, 1995. 

Giant cell tumor of the tendon sheath, also known as the localized form of pigmented villonodu-lar synovitis, is the second most common space-occupying lesion of the hand. It occurs most frequently in patients 30-50 years old and appears as an extra-articular painless and slow-growing solid hypoechoic mass with sharp margins, located on the volar aspect of the fingers with lateral and... 

Kobata, A., 1989, Altered glycosylation of surface glycoproteins in tumor cells and its clinical application. Pigment Cell Res. 2 304-308. 

Erythrocytes from humans, birds, and rat Ehrlich ascites tumor cells astrocytes fibroblasts C67 glioma cells intestine trachea parotid MDCK cells retinal pigment epithelium frog skin HeLa cells rabbit medullary thick ascending limb Inhibition of K+ and Cl channels... 

The major pigment in Curcuma species (Zingiberaceae family) is the yellow phenolic diarylheptanoid curcumin (Jl). Curcumin and its analogs have potent antioxidant and antiinflammatory effects, cytotoxicity against tumor cells, and antitumor-promoting activity (96). The biologic effects and targets of curcumin, as well as its possible roles in cancer prevention and therapy, have been reviewed recently (97, 98). 

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